SCHEMBL896767

SCHEMBL896767

Cc1cc(S(=O)(=O)c2cc(C)c(F)c(C)c2)cc(C)c1F

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SOS1 Q07889 1/20 0.44
GAA P10253 1/20 0.40
TRPA1 O75762 6/20 0.38
LMNA P02545 2/20 0.38
TDP1 Q9NUW8 1/20 0.38
TSHR P16473 3/20 0.37
POLB P06746 2/20 0.37
MAPK1 P28482 1/20 0.37
HTR6 P50406 2/20 0.36
RAPGEF4 Q8WZA2 1/20 0.35
ALDH1A1 P00352 2/20 0.35
MAPT P10636 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
FFAR4 Q5NUL3 1/20 0.34
VCAM1 P19320 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2123970 1.00 SOS1 (0.44) SOS1GAATRPA1LMNATDP1
SCHEMBL6180421 0.80 SOS1 (0.42) SOS1TRPA1LMNATDP1TSHR
SCHEMBL16081307 0.80 SOS1 (0.42) SOS1GAATRPA1LMNATDP1
SCHEMBL9001244 0.78 GAA (0.43) GAALMNATDP1TSHRPOLB
SCHEMBL359985 0.74 CA1 (0.50) GAALMNARAPGEF4ALDH1A1MAPT
SCHEMBL4136925 0.74 HDAC1 (0.40) GAATSHRPOLBMAPK1HTR6
SCHEMBL2122582 0.74 CYP3A4 (0.46) GAALMNATDP1POLBMAPK1
SCHEMBL896459 0.74 CYP3A4 (0.46) GAALMNATDP1POLBMAPK1
SCHEMBL142565 0.74 CA1 (0.50) GAALMNARAPGEF4ALDH1A1MAPT
SCHEMBL8400822 0.74 GAA (0.40) GAALMNATDP1TSHRPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111770786-A Removal of metal ions with membranes based on anionic polyarylene ether sulfones and cationic polymers with amino groups 杜邦安全与建筑公司 2020-10-13 CN disclosed
EP-2443172-B1 AROMATIC POLYETHERSULFONE BLOCK COPOLYMERS BASF SE (DE) 2016-09-21 EP disclosed
CN-104245102-B The composite membrane of high performance tape positive electricity and the purposes in nano filtering process thereof 巴斯夫欧洲公司 2016-06-22 CN disclosed
US-9199205-B2 Ultrafiltration membranes fabricated from sulfonated polyphenylenesulfones BASF SE (DE) 2015-12-01 US disclosed
US-9120062-B2 High performance positively charged composite membranes and their use in nanofiltration processes BASF SE (DE) 2015-09-01 US disclosed
CN-104540580-A Composite membranes comprising sulfonated polyphenylsulfone and their use in forward osmosis processes BASF SE 2015-04-22 CN disclosed
CN-104411388-A Ultrafiltration membranes prepared from sulfonated polyphenylene sulfones BASF SE 2015-03-11 CN disclosed
CN-104245102-A HIGH PERFORMANCE POSITIVELY CHARGED COMPOSITE MEMBRANES AND THEIR USE IN NANOFILTRATION PROCESSES BASF SE 2014-12-24 CN disclosed
US-20130341273-A1 COMPOSITE MEMBRANES COMPRISING SULFONATED POLYPHENYLENESULFONE AND THEIR USE IN FORWARD OSMOSIS PROCESSES NATIONAL UNIVERSITY OF SINGAPORE (SG) 2013-12-26 US disclosed
US-20130306551-A1 HIGH PERFORMANCE POSITIVELY CHARGED COMPOSITE MEMBRANES AND THEIR USE IN NANOFILTRATION PROCESSES NATIONAL UNIVERSITY OF SINGAPORE (SG) 2013-11-21 US disclosed
US-7258941-B2 Polymer electrolyte for solid polymer type fuel cell and fuel cell UBE INDUSTRIES, LTD. (JP) 2007-08-21 US disclosed
EP-1394879-B1 POLYMER ELECTROLYTE FOR SOLID POLYMER TYPE FUEL CELL AND FUEL CELL UBE INDUSTRIES (JP) 2006-08-23 EP disclosed
US-20060115695-A1 Bisphenol compound and aromatic polyaryl ether UBE INDUSTRIES, LTD. (JP) 2006-06-01 US disclosed
US-20050069780-A1 Aromatic polymer with either carbonyl and/or sulfone groups and cationic group for conductivity and anhydrous or solvent UBE INDUSTRIES, LTD (JP) 2005-03-31 US disclosed
EP-1449886-A1 POLYELECTROLYTE COMPOSITIONS Ube Industries, Ltd. (JP) 2004-08-25 EP disclosed
US-20040101730-A1 Polymer electrolyte for solid polymer type fuel cell and fuel cell UBE INDUSTRIES, LTD. (JP) 2004-05-27 US disclosed
EP-1394879-A1 POLYMER ELECTROLYTE FOR SOLID POLYMER TYPE FUEL CELL AND FUEL CELL Ube Industries, Ltd. (JP) 2004-03-03 EP disclosed
EP-0237593-B1 AROMATIC POLYSULFONE ETHER/POLYTHIOETHER SULFONE COPOLYMER AND PROCESS FOR ITS PREPARATION ASAHI GLASS COMPANY LTD. (JP) 1990-07-04 EP disclosed
EP-0237593-A1 Aromatic polysulfone ether/polythioether sulfone copolymer and process for its preparation ASAHI GLASS COMPANY LTD. (JP) 1987-09-23 EP disclosed
US-4654410-A MOLDING MATERIALS ASAHI GLASS COMPANY, LTD. (JP) 1987-03-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060115695-A1 Bisphenol compound and aromatic polyaryl ether ARSA, EP300, PAH SOS1 2592/4885GAA 2361/4885TRPA1 1365/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.