SCHEMBL896459

SCHEMBL896459

Cc1cc(S(=O)(=O)c2cc(C)c(Cl)c(C)c2)cc(C)c1Cl

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.46
ALOX15 P16050 2/20 0.46
CHRM1 P11229 1/20 0.46
MAOA P21397 1/20 0.46
TBXA2R P21731 1/20 0.46
ADRA1A P35348 1/20 0.46
HTR2B P41595 1/20 0.46
ALDH1A1 P00352 4/20 0.40
GAA P10253 2/20 0.40
MAPK1 P28482 1/20 0.40
FFAR4 Q5NUL3 3/20 0.38
LMNA P02545 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
PKM P14618 1/20 0.36
HTR6 P50406 2/20 0.36
RAPGEF4 Q8WZA2 1/20 0.35
POLB P06746 1/20 0.35
MAPT P10636 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
HPGD P15428 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2122582 1.00 CYP3A4 (0.46) CYP3A4ALOX15CHRM1MAOATBXA2R
SCHEMBL8764095 0.80 CA2 (0.52) CYP3A4ALOX15CHRM1MAOATBXA2R
SCHEMBL9001244 0.78 GAA (0.43) ALDH1A1GAAMAPK1FFAR4LMNA
SCHEMBL28001568 0.77 CYP3A4 (0.39) CYP3A4ALOX15CHRM1MAOATBXA2R
SCHEMBL940947 0.75 CA1 (0.52) CYP3A4ALDH1A1LMNATDP1POLB
SCHEMBL2123970 0.74 SOS1 (0.44) ALDH1A1GAAMAPK1FFAR4LMNA
SCHEMBL359985 0.74 CA1 (0.50) CYP3A4ALDH1A1GAALMNAPKM
SCHEMBL8400822 0.74 GAA (0.40) ALDH1A1GAAMAPK1LMNATDP1
SCHEMBL142565 0.74 CA1 (0.50) CYP3A4ALDH1A1GAALMNAPKM
SCHEMBL896767 0.74 SOS1 (0.44) ALDH1A1GAAMAPK1FFAR4LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210178342-A1 REMOVING METAL IONS WITH A MEMBRANE BASED ON ANIONIC POLYARYLENE ETHERSULFONE AND A CATIONIC POLYMER WITH AMINO GROUPS DUPONT SAFETY & CONSTRUCTION INC (US) 2021-06-17 US disclosed
EP-3723896-A1 REMOVING METAL IONS WITH A MEMBRANE BASED ON ANIONIC POLYARYLENE ETHERSULFONE AND A CATIONIC POLYMER WITH AMINO GROUPS DuPont Safety & Construction, Inc. (US) 2020-10-21 EP disclosed
CN-111770786-A Removal of metal ions with membranes based on anionic polyarylene ether sulfones and cationic polymers with amino groups 杜邦安全与建筑公司 2020-10-13 CN disclosed
US-20200246761-A1 NANOFILTRATION COMPOSITE MEMBRANES COMPRISING SELF-ASSEMBLED SUPRAMOLECULAR SEPARATION LAYER BASF SE (DE) 2020-08-06 US disclosed
WO-2019115274-A1 REMOVING METAL IONS WITH A MEMBRANE BASED ON ANIONIC POLYARYLENE ETHERSULFONE AND A CATIONIC POLYMER WITH AMINO GROUPS BASF SE (DE) 2019-06-20 WO disclosed
EP-3377200-A1 NANOFILTRATION COMPOSITE MEMBRANES COMPRISING SELF-ASSEMBLED SUPRAMOLECULAR SEPARATION LAYER BASF SE (DE) 2018-09-26 EP disclosed
EP-2443172-B1 AROMATIC POLYETHERSULFONE BLOCK COPOLYMERS BASF SE (DE) 2016-09-21 EP disclosed
EP-2838646-B1 HIGH PERFORMANCE POSITIVELY CHARGED COMPOSITE NANOFILTRATION MEMBRANE AND ITS PREPARATION BASF SE (DE) 2016-03-23 EP disclosed
US-9199205-B2 Ultrafiltration membranes fabricated from sulfonated polyphenylenesulfones BASF SE (DE) 2015-12-01 US disclosed
US-9120062-B2 High performance positively charged composite membranes and their use in nanofiltration processes BASF SE (DE) 2015-09-01 US disclosed
US-5008364-A Includes alkal; metal salts BASF AKTIENGESELLSCHAFT (DE) 1991-04-16 US disclosed
US-4960841-A REACTING A PREPOLYMER WITH A MIXTURE OF A DIHALODIPHENYL-SULFONE OR A HALOGENATED AROMATIC COMPOUND AND A SULFIDIZATION AGENT IN A POLAR SOLVENT DAINIPPON INK AND CHEMICALS, INC. (JP) 1990-10-02 US disclosed
EP-0237593-B1 AROMATIC POLYSULFONE ETHER/POLYTHIOETHER SULFONE COPOLYMER AND PROCESS FOR ITS PREPARATION ASAHI GLASS COMPANY LTD. (JP) 1990-07-04 EP disclosed
US-4929665-A POLYSULFIDES AND POLYPHENYLENE SULFIDE SULFONES DAINIPPON INK AND CHEMICALS, INC. (JP) 1990-05-29 US disclosed
US-4925910-A POLYETHERSULFONES BASF AKTIENGESELLSCHAFT (DE) 1990-05-15 US disclosed
US-4904754-A PRINTED CIRCUITS, ELECTRIC PLUGS BASF AKTIENGESELLSCHAFT (DE) 1990-02-27 US disclosed
US-4762869-A BLOCK POLYETHERS WITH SULFONES AND CARBONYLS BASF AKTIENGESELLSCHAFT (DE) 1988-08-09 US disclosed
EP-0268765-A2 Resin comprising a polyphenylene sulfide/polyphenylene sulfone block copolymer, process for preparing the copolymer and molded article DAINIPPON INK AND CHEMICALS, INC. (JP) 1988-06-01 EP disclosed
EP-0237593-A1 Aromatic polysulfone ether/polythioether sulfone copolymer and process for its preparation ASAHI GLASS COMPANY LTD. (JP) 1987-09-23 EP disclosed
US-4654410-A MOLDING MATERIALS ASAHI GLASS COMPANY, LTD. (JP) 1987-03-31 US disclosed