Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | RAPGEF4 | Q8WZA2 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 6/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9001244 | 0.78 | GAA (0.43) | GAALMNATDP1RAPGEF4ALDH1A1 | |
| SCHEMBL896459 | 0.74 | CYP3A4 (0.46) | GAALMNATDP1RAPGEF4ALDH1A1 | |
| SCHEMBL2123970 | 0.74 | SOS1 (0.44) | GAALMNATDP1RAPGEF4ALDH1A1 | |
| SCHEMBL359985 | 0.74 | CA1 (0.50) | GAALMNARAPGEF4ALDH1A1MAPT | |
| SCHEMBL3947257 | 0.74 | ALDH1A1 (0.50) | GAALMNATDP1RAPGEF4ALDH1A1 | |
| SCHEMBL2122582 | 0.74 | CYP3A4 (0.46) | GAALMNATDP1RAPGEF4ALDH1A1 | |
| SCHEMBL896767 | 0.74 | SOS1 (0.44) | GAALMNATDP1RAPGEF4ALDH1A1 | |
| SCHEMBL142565 | 0.74 | CA1 (0.50) | GAALMNARAPGEF4ALDH1A1MAPT | |
| SCHEMBL8400899 | 0.70 | POLB (0.43) | GAALMNATDP1RAPGEF4ALDH1A1 | |
| SCHEMBL8137089 | 0.69 | GAA (0.52) | GAALMNARAPGEF4ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120129076-A1 | Novel Sulfonic Acid Group-Containing Segmented Block Copolymer and Use Thereof | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 2012-05-24 | — | — | US | disclosed |