Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.56 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.56 |
| ▸ | BAX | Q07812 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.52 |
| ▸ | XIAP | P98170 | 1/20 | 0.49 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7176453 | 0.89 | DPP4 (0.53) | XIAPDPP4MAPK14MAPK1ALDH1A1 | |
| SCHEMBL4211500 | 0.84 | LTA4H (0.68) | LTA4HNR1H2BAXMEN1KMT2A | |
| SCHEMBL11402635 | 0.84 | MEN1 (0.48) | LTA4HNR1H2BAXMEN1KMT2A | |
| SCHEMBL9321769 | 0.83 | HTR2A (0.53) | MEN1KMT2AXIAPDPP4MAPK1 | |
| SCHEMBL3790160 | 0.82 | DPP4 (0.62) | LTA4HNR1H2KMT2AXIAPDPP4 | |
| SCHEMBL9483870 | 0.82 | LTA4H (0.73) | LTA4HNR1H2BAXMEN1KMT2A | |
| SCHEMBL9588305 | 0.80 | LTA4H (0.77) | LTA4HNR1H2BAXMEN1KMT2A | |
| Ammonia Solution, Strong SCHEMBL4267774 | 0.80 | DPP4 (0.60) | LTA4HNR1H2MEN1KMT2AXIAP | |
| SCHEMBL11738686 | 0.79 | SLC6A2 (0.50) | XIAPDPP4MAPK14MAPK1ALDH1A1 | |
| SCHEMBL5023569 | 0.79 | SLC6A4 (0.51) | XIAPDPP4MAPK1ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1869028-A | Preparation method of 2-(4-hydroxy benzoxy) 6-chlorobenzene diozaiole | CHEN KEFU (CN) | 2006-11-29 | — | — | CN | claimed |
| EP-0306051-B1 | Process for production of aromatic polyethers | MITSUBISHI GAS CHEMICAL CO (JP) | 1996-03-06 | — | — | EP | disclosed |
| CN-1082023-A | The medicine and the novel benzoic acid derivative that contain benzoic acid derivative | YAMANOUCHI PHARMA CO LTD (JP) | 1994-02-16 | — | — | CN | disclosed |
| US-4952665-A | Process for production of aromatic polyethers with alkali metal carbonate/bicarbonate/fluoride cocatalyst | MITSUBISHI GAS CHEMICAL COMPANY, LTD. (JP) | 1990-08-28 | — | — | US | disclosed |
| EP-0306051-A1 | Process for production of aromatic polyethers | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1989-03-08 | — | — | EP | disclosed |
| EP-0033614-B1 | PHENYLALKANOIC ACID DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-06-06 | — | — | EP | disclosed |
| US-4391995-A | 4-Phenoxy-phenoxy-alkane-carboxylic acid derivatives and process for their manufacture | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-07-05 | — | — | US | disclosed |
| US-4367238-A | ANTIINFLAMMATORY AGENTS, ANALGESICS | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1983-01-04 | — | — | US | disclosed |
| US-4301295-A | ANTILIPEMIC AND ANTICHOLESTEROL AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-11-17 | — | — | US | disclosed |
| EP-0033614-A1 | Phenylalkanoic acid derivatives, processes for the preparation thereof and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-08-12 | — | — | EP | disclosed |
| US-4254262-A | IN THE PRESENCE OF A QUATERNARY AMMONIUM OR PHOSPHONIUM SALT | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 1981-03-03 | — | — | US | disclosed |
| US-4238626-A | ANTICHOLESTEROL AND ANTILIPEMIC AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-12-09 | — | — | US | disclosed |