Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 0.51 |
| ▸ | HTR2A | P28223 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | XIAP | P98170 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7176453 | 0.89 | DPP4 (0.53) | SLC6A4LMNAXIAPL3MBTL1HTT | |
| SCHEMBL11795870 | 0.88 | XIAP (0.48) | SLC6A4HTR2ALMNAXIAPHTT | |
| SCHEMBL2608310 | 0.84 | HTT (0.65) | SLC6A4HTR2ALMNAL3MBTL1HTT | |
| SCHEMBL14649873 | 0.83 | L3MBTL1 (0.61) | SLC6A4LMNAXIAPL3MBTL1HTT | |
| SCHEMBL9321769 | 0.83 | HTR2A (0.53) | SLC6A4HTR2AXIAPL3MBTL1HTT | |
| Ethane SCHEMBL27569819 | 0.83 | DPP4 (0.58) | SLC6A4LMNAXIAPL3MBTL1HTT | |
| SCHEMBL3790160 | 0.82 | DPP4 (0.62) | SLC6A4LMNAXIAPL3MBTL1HTT | |
| SCHEMBL14649862 | 0.81 | TLR8 (0.54) | SLC6A4HTR2ALMNAXIAPL3MBTL1 | |
| Ammonia Solution, Strong SCHEMBL4267774 | 0.80 | DPP4 (0.60) | SLC6A4LMNAXIAPL3MBTL1ALDH1A1 | |
| SCHEMBL11585106 | 0.80 | ALDH1A1 (0.60) | SLC6A4HTR2ALMNAL3MBTL1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024105364-A1 | HETEROCYCLIC INHIBITORS OF CDC-LIKE KINASES | CURADEV PHARMA LTD (GB) | 2024-05-23 | — | — | WO | disclosed |
| WO-2021061929-A1 | BICYCLIC CARBOXYLATES AS MODULATORS OF TRANSPORTERS AND USES THEREOF | Nirogy Therapeutics, Inc. (US) | 2021-04-01 | — | — | WO | disclosed |
| EP-2871180-B1 | 2-AMINONICOTINIC ACID ESTER DERIVATIVE AND BACTERICIDE CONTAINING SAME AS ACTIVE INGREDIENT | AGRO KANESHO CO LTD (JP) | 2018-03-21 | — | — | EP | disclosed |
| US-9096528-B2 | 2-aminonicotinic acid ester derivative and bactericide containing same as active ingredient | AGRO-KANESHO CO., LTD. (JP) | 2015-08-04 | — | — | US | disclosed |
| US-20150175551-A1 | 2-AMINONICOTINIC ACID ESTER DERIVATIVE AND BACTERICIDE CONTAINING SAME AS ACTIVE INGREDIENT | AGRO-KANESHO CO., LTD. (JP) | 2015-06-25 | — | — | US | disclosed |
| US-20150175551-A1 | 2-AMINONICOTINIC ACID ESTER DERIVATIVE AND BACTERICIDE CONTAINING SAME AS ACTIVE INGREDIENT | AGRO-KANESHO CO., LTD. (JP) | 2015-06-25 | — | — | US | disclosed |
| CN-102712202-A | Heat-sensitive lithographic printing plate and printing method thereof | MITSUBISHI PAPER MILLS LTD | 2012-10-03 | — | — | CN | disclosed |
| US-8178490-B2 | Polybasic bacterial efflux pump inhibitors and therapeutic uses thereof | REMPEX PHARMACEUTICALS, INC. (US) | 2012-05-15 | — | — | US | disclosed |
| US-20100152098-A1 | POLYBASIC BACTERIAL EFFLUX PUMP INHIBITORS AND THERAPEUTIC USES THEREOF | MPEX PHARMACEUTICALS, INC. (US) | 2010-06-17 | — | — | US | disclosed |
| WO-2007113327-A2 | FUNGICIDE N-CYCLOPROPYL-SULFONYLAMIDE DERIVATIVES | BAYER CROPSCIENCE SA (FR) | 2007-10-11 | — | — | WO | disclosed |
| US-4203145-A | Chloro-diphenyl | BAYER AKTIENGESELLSCHAFT (DE) | 1980-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152098-A1 | POLYBASIC BACTERIAL EFFLUX PUMP INHIBITORS AND THERAPEUTIC USES THEREOF | ABCB11, ABCB1, SLC47A1 | SLC6A4 1283/4885HTR2A 4677/4885LMNA 3488/4885 |
| US-20150175551-A1 | 2-AMINONICOTINIC ACID ESTER DERIVATIVE AND BACTERICIDE CONTAINING SAME AS ACTIVE INGREDIENT | HDHD5, BCAT1, ACMSD | SLC6A4 1305/4885HTR2A 334/4885LMNA 1901/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.