SCHEMBL8967798

SCHEMBL8967798

O=C(c1ccc(Cl)cc1)c1ccc(Sc2ccc(O)cc2)cc1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.77
HPGD P15428 3/20 0.58
LMNA P02545 3/20 0.58
MAPT P10636 2/20 0.58
ESR1 P03372 1/20 0.58
ESR2 Q92731 1/20 0.58
PKM P14618 1/20 0.58
HTT P42858 1/20 0.58
NR1H2 P55055 1/20 0.54
SRD5A2 P31213 2/20 0.53
RAB9A P51151 2/20 0.49
NPC1 O15118 1/20 0.49
CXCL12 P48061 1/20 0.46
CNR1 P21554 1/20 0.46
CNR2 P34972 1/20 0.46
MAOB P27338 1/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.45
CTRC Q99895 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8967091 0.92 SRD5A2 (0.61) MAPK1HPGDLMNAMAPTSRD5A2
SCHEMBL9475945 0.92 SRD5A2 (0.61) MAPK1HPGDLMNAMAPTSRD5A2
SCHEMBL9134344 0.90 LMNA (0.71) MAPK1HPGDLMNAMAPTESR1
SCHEMBL4563922 0.90 LMNA (0.71) MAPK1HPGDLMNAMAPTESR1
SCHEMBL9457019 0.88 MAPK1 (1.00) MAPK1HPGDLMNAMAPTESR1
Hydroquinone SCHEMBL10635396 0.88 MAPK1 (1.00) MAPK1HPGDLMNAMAPTESR1
SCHEMBL333466 0.88 MAPK1 (1.00) MAPK1HPGDLMNAMAPTESR1
Hydroquinone SCHEMBL9777901 0.88 MAPK1 (1.00) MAPK1HPGDLMNAMAPTESR1
SCHEMBL9777896 0.88 MAPK1 (1.00) MAPK1HPGDLMNAMAPTESR1
SCHEMBL9777899 0.86 MAPK1 (0.95) MAPK1HPGDLMNAMAPTESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0306051-B1 Process for production of aromatic polyethers MITSUBISHI GAS CHEMICAL CO (JP) 1996-03-06 EP claimed
EP-0306051-A1 Process for production of aromatic polyethers MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1989-03-08 EP claimed
EP-0306051-B1 Process for production of aromatic polyethers MITSUBISHI GAS CHEMICAL CO (JP) 1996-03-06 EP disclosed
US-4952665-A Process for production of aromatic polyethers with alkali metal carbonate/bicarbonate/fluoride cocatalyst MITSUBISHI GAS CHEMICAL COMPANY, LTD. (JP) 1990-08-28 US disclosed
EP-0306051-A1 Process for production of aromatic polyethers MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1989-03-08 EP disclosed