Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 13/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 13/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 12/20 | 0.41 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MC4R | P32245 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17605050 | 0.82 | SIGMAR1 (0.53) | SIGMAR1POLB | |
| SCHEMBL17605151 | 0.82 | SIGMAR1 (0.53) | SIGMAR1POLB | |
| SCHEMBL17605544 | 0.82 | SIGMAR1 (0.53) | SIGMAR1POLB | |
| SCHEMBL9390747 | 0.79 | SIGMAR1 (0.50) | SIGMAR1POLB | |
| SCHEMBL17605316 | 0.79 | SIGMAR1 (0.50) | SIGMAR1POLB | |
| SCHEMBL17604761 | 0.79 | SIGMAR1 (0.50) | SIGMAR1POLB | |
| SCHEMBL17605508 | 0.79 | SIGMAR1 (0.50) | SIGMAR1POLB | |
| SCHEMBL23023176 | 0.78 | EPHX2 (0.50) | SIGMAR1POLB | |
| SCHEMBL8907879 | 0.78 | EPHX2 (0.50) | SIGMAR1POLB | |
| Hydrochloric Acid SCHEMBL17605202 | 0.78 | SIGMAR1 (0.49) | SIGMAR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0697015-A1 | OPTICALLY ACTIVE 3-(1-(ALKYLAMINO))ALKYL PYRROLIDINES | PHARMACIA & UPJOHN COMPANY (US) | 1996-02-21 | — | — | EP | disclosed |