Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.43 |
| ▸ | ITGAV | P06756 | 1/20 | 0.43 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23023176 | 1.00 | EPHX2 (0.50) | EPHX2SIGMAR1EPHX1HPGDRAB9A | |
| SCHEMBL9390747 | 0.98 | SIGMAR1 (0.50) | EPHX2SIGMAR1EPHX1HPGDRAB9A | |
| SCHEMBL17605316 | 0.95 | SIGMAR1 (0.50) | EPHX2SIGMAR1EPHX1HPGDALDH1A1 | |
| SCHEMBL17604761 | 0.95 | SIGMAR1 (0.50) | EPHX2SIGMAR1EPHX1HPGDALDH1A1 | |
| SCHEMBL17605508 | 0.95 | SIGMAR1 (0.50) | EPHX2SIGMAR1EPHX1HPGDALDH1A1 | |
| Hydrochloric Acid SCHEMBL17605202 | 0.93 | SIGMAR1 (0.49) | EPHX2SIGMAR1EPHX1HPGDRAB9A | |
| SCHEMBL17605151 | 0.91 | SIGMAR1 (0.53) | EPHX2SIGMAR1POLBSMN1; SMN2KMT2A | |
| SCHEMBL17605544 | 0.91 | SIGMAR1 (0.53) | EPHX2SIGMAR1POLBSMN1; SMN2KMT2A | |
| SCHEMBL17605050 | 0.91 | SIGMAR1 (0.53) | EPHX2SIGMAR1POLBSMN1; SMN2KMT2A | |
| SCHEMBL23022872 | 0.85 | SIGMAR1 (0.47) | EPHX2SIGMAR1EPHX1HPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210053997-A1 | TRNA SYNTHETASE INHIBITORS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2021-02-25 | — | — | US | disclosed |
| US-5686616-A | Process for preparing an optically active amine | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1997-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210053997-A1 | TRNA SYNTHETASE INHIBITORS | TRMT1, AARS1, GARS1 | EPHX2 3395/4885SIGMAR1 2321/4885EPHX1 3417/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.