SCHEMBL8967952

SCHEMBL8967952

Nc1ccc(-c2ccc(C(=O)O)cc2N)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.49
GAA P10253 6/20 0.49
ALDH1A1 P00352 4/20 0.49
MAPT P10636 4/20 0.49
HPGD P15428 4/20 0.49
GFER P55789 3/20 0.49
POLB P06746 2/20 0.49
TDP1 Q9NUW8 2/20 0.49
CSNK2A2 P19784 1/20 0.49
CSNK2B P67870 1/20 0.49
CSNK2A1 P68400 1/20 0.49
CSNK2A3 Q8NEV1 1/20 0.49
NPC1 O15118 1/20 0.49
MITF O75030 1/20 0.49
NFKB1 P19838 1/20 0.49
RECQL P46063 1/20 0.49
RAB9A P51151 1/20 0.49
NFKB2 Q00653 1/20 0.49
RELA Q04206 1/20 0.49
PAX8 Q06710 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26981140 0.94 KDM4E (0.50) KDM4EGAAALDH1A1MAPTHPGD
SCHEMBL15901215 0.92 MAP4K4 (0.49) KDM4EGAAALDH1A1MAPTHPGD
SCHEMBL30073619 0.91 MAP4K4 (0.51) KDM4EGAAPOLBTDP1HSD17B10
SCHEMBL31207231 0.89 MAP4K4 (0.50) KDM4EGAAPOLBTDP1HSD17B10
SCHEMBL28866055 0.87 HSD17B10 (0.53) KDM4EGAAMAPTPOLBTDP1
SCHEMBL3098750 0.87 ALDH1A1 (0.53) KDM4EGAAALDH1A1MAPTHPGD
SCHEMBL14972646 0.87 CSNK2A2 (0.54) KDM4EGAAALDH1A1MAPTHPGD
SCHEMBL17177739 0.86 KDM4E (0.50) KDM4EGAAALDH1A1MAPTHPGD
SCHEMBL28389674 0.86 KDM4E (0.56) KDM4EGAAALDH1A1MAPTHPGD
SCHEMBL3790168 0.85 PARP10 (0.47) KDM4EALDH1A1TDP1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5571579-A FORMING A POLYIMIDE FILM AND RUBBING THE SURFACE OF THE FILM HITACHI CHEMICAL COMPANY, LTD (JP) 1996-11-05 US disclosed