Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.70 |
| ▸ | DAO | P14920 | 1/20 | 0.70 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.70 |
| ▸ | CES2 | O00748 | 3/20 | 0.58 |
| ▸ | CES1 | P23141 | 3/20 | 0.58 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.58 |
| ▸ | AKT1 | P31749 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | KMO | O15229 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL27616171 | 0.87 | TSHR (0.74) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL997600 | 0.87 | TSHR (0.74) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL28775769 | 0.85 | TSHR (0.70) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL9644655 | 0.85 | TSHR (0.70) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL30978335 | 0.85 | TSHR (0.70) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL28553415 | 0.85 | TSHR (0.70) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL10493461 | 0.85 | TSHR (0.70) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL4158962 | 0.85 | TSHR (0.70) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL9399693 | 0.85 | TSHR (0.70) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL1434863 | 0.85 | TSHR (0.70) | TSHRDAONAPRTCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118256210-A | Degradable liquid steering agent and preparation method thereof | 中国石油化工股份有限公司 | 2024-06-28 | — | — | CN | claimed |
| CN-118255916-A | Broad-spectrum temporary plugging agent and preparation method thereof | 中国石油化工股份有限公司 | 2024-06-28 | — | — | CN | claimed |
| CN-112533997-B | Hydrogels and uses thereof | 积水化成品工业株式会社 | 2023-09-26 | — | — | CN | claimed |
| CN-115572342-A | Copolymer cement additive with conjugated cyclic high-temperature resistance and preparation method thereof | 淮阴工学院 | 2023-01-06 | — | — | CN | claimed |
| CN-115521088-A | Preparation method of attapulgite compounded conjugated annular high-temperature-resistant copolymer cement additive | 淮阴工学院 | 2022-12-27 | — | — | CN | claimed |
| EP-0471116-B1 | A polymer useful for drag reduction in hydrocarbon fluids and its preparations | COUNCIL SCIENT IND RES (IN) | 1996-03-06 | — | — | EP | claimed |
| EP-0471116-A1 | A polymer useful for drag reduction in hydrocarbon fluids and its preparations | Council of Scientific & Industrial Research (IN) | 1992-02-19 | — | — | EP | claimed |
| US-5080121-A | Acrylate and ionic monomer | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 1992-01-14 | — | — | US | claimed |
| CN-122060716-A | Preparation method of nano enzyme material, composite composition and application thereof | 厦门瑞聚医学科技有限公司 | 2026-05-19 | — | — | CN | disclosed |
| CN-122005907-A | Enzyme polymer composite composition and application thereof | 厦门瑞聚医学科技有限公司 | 2026-05-12 | — | — | CN | disclosed |
| CN-112533997-B | Hydrogels and uses thereof | 积水化成品工业株式会社 | 2023-09-26 | — | — | CN | disclosed |
| CN-115572342-A | Copolymer cement additive with conjugated cyclic high-temperature resistance and preparation method thereof | 淮阴工学院 | 2023-01-06 | — | — | CN | disclosed |
| CN-115521088-A | Preparation method of attapulgite compounded conjugated annular high-temperature-resistant copolymer cement additive | 淮阴工学院 | 2022-12-27 | — | — | CN | disclosed |
| CN-113402667-A | Selective absorption material and preparation method and application thereof | 华东师范大学 | 2021-09-17 | — | — | CN | disclosed |
| CN-107207851-B | Method for producing photochromic cured product | 株式会社德山 | 2020-07-17 | — | — | CN | disclosed |
| CN-101784568-B | Polyrotaxane, crosslinked structure comprising polyrotaxane and polymer, and processes for producing these | ADVANCED SOFTMATERIALS INC | 2014-03-26 | — | — | CN | disclosed |
| CN-101784568-A | Polyrotaxane, crosslinked structure comprising polyrotaxane and polymer, and processes for producing these | ADVANCED SOFTMATERIALS INC | 2010-07-21 | — | — | CN | disclosed |
| EP-0471116-B1 | A polymer useful for drag reduction in hydrocarbon fluids and its preparations | COUNCIL SCIENT IND RES (IN) | 1996-03-06 | — | — | EP | disclosed |
| EP-0471116-A1 | A polymer useful for drag reduction in hydrocarbon fluids and its preparations | Council of Scientific & Industrial Research (IN) | 1992-02-19 | — | — | EP | disclosed |
| US-5080121-A | Acrylate and ionic monomer | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 1992-01-14 | — | — | US | disclosed |