Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.70 |
| ▸ | DAO | P14920 | 1/20 | 0.70 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.70 |
| ▸ | CES2 | O00748 | 4/20 | 0.58 |
| ▸ | CES1 | P23141 | 4/20 | 0.58 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.58 |
| ▸ | AKT1 | P31749 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | KMO | O15229 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL1434863 | 1.00 | TSHR (0.70) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL9644655 | 1.00 | TSHR (0.70) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL11340972 | 0.98 | TSHR (0.67) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL21145058 | 0.98 | TSHR (0.67) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL2921097 | 0.91 | TSHR (0.58) | TSHRDAONAPRTCES2CES1 | |
| Terephthalic Acid SCHEMBL15050 | 0.90 | TSHR (0.67) | TSHRDAONAPRTCES2CES1 | |
| Terephthalic Acid SCHEMBL28737896 | 0.90 | TSHR (0.67) | TSHRDAONAPRTCES2CES1 | |
| Terephthalic Acid SCHEMBL16470220 | 0.90 | TSHR (0.67) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL15300262 | 0.87 | TSHR (0.74) | TSHRDAONAPRTCES2CES1 | |
| Terephthalic Acid SCHEMBL11664464 | 0.87 | TSHR (0.63) | TSHRDAONAPRTCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102405131-A | Indicator for detecting the presence of microbial metabolic byproducts | INDICATOR SYSTEMS INTERNATIONA | 2012-04-04 | — | — | CN | claimed |
| EP-1112174-B1 | ISOSORBIDE CONTAINING POLYESTERS AND METHODS FOR MAKING SAME | DU PONT (US) | 2009-07-01 | — | — | EP | claimed |
| US-20260146118-A1 | ACETALIZATION PRODUCT OF ETHYLENEVINYL ALCOHOL COPOLYMER, COMPOSITION CONTAINING SAID ACETALIZATION PRODUCT, AND BARRIER MATERIAL | KURARAY CO., LTD. (JP) | 2026-05-28 | — | — | US | disclosed |
| EP-4606825-A1 | ACETALIZATION PRODUCT OF ETHYLENEVINYL ALCOHOL COPOLYMER, COMPOSITION CONTAINING SAID ACETALIZATION PRODUCT, AND BARRIER MATERIAL | Kuraray Co., Ltd. (JP) | 2025-08-27 | — | — | EP | disclosed |
| WO-2024085035-A1 | ACETALIZATION PRODUCT OF ETHYLENEVINYL ALCOHOL COPOLYMER, COMPOSITION CONTAINING SAID ACETALIZATION PRODUCT, AND BARRIER MATERIAL | 株式会社クラレ | 2024-04-25 | — | — | WO | disclosed |
| CN-113710710-A | Method for producing propylene polymer | 住友化学株式会社 | 2021-11-26 | — | — | CN | disclosed |
| EP-2726447-B1 | PROCESS FOR THE PREPARATION OF BETA-SANTALOL | FIRMENICH & CIE (CH) | 2015-08-12 | — | — | EP | disclosed |
| US-9056826-B2 | Process for the preparation of beta-santalol | FIRMENICH SA (CH) | 2015-06-16 | — | — | US | disclosed |
| US-20140213818-A1 | PROCESS FOR THE PREPARATION OF BETA-SANTALOL | FIRMENICH SA (CH) | 2014-07-31 | — | — | US | disclosed |
| EP-2726447-A1 | PROCESS FOR THE PREPARATION OF BETA-SANTALOL | Firmenich SA (CH) | 2014-05-07 | — | — | EP | disclosed |
| WO-2013001026-A1 | PROCESS FOR THE PREPARATION OF BETA-SANTALOL | FIRMENICH SA (CH) | 2013-01-03 | — | — | WO | disclosed |
| US-6759107-B1 | THERMOPLASTIC RESIN, TRANSITION METAL SALT, MULTILAYERED POLYMER PARTICLE COMPRISING A CONJUGATED DIENE MONOMER | KURARAY CO., LTD. (JP) | 2004-07-06 | — | — | US | disclosed |
| CN-1487905-A | Sized glass yarns, sizing compositions and composites containing said yarns | ����ʥ���Τ������˹����˾ | 2004-04-07 | — | — | CN | disclosed |
| EP-1067154-A2 | Thermoplastic resin composition and multilayered container using the same | Kuraray Co., Ltd. (JP) | 2001-01-10 | — | — | EP | disclosed |
| US-5574078-A | INK COLOR CONCENTRATES WITH IONOMERS FOR INKS | LASERMASTER CORPORATION (US) | 1996-11-12 | — | — | US | disclosed |
| EP-0165383-B1 | RESINOUS COMPOSITION | KURARAY CO., LTD. (JP) | 1993-06-09 | — | — | EP | disclosed |
| US-4774114-A | FOR CARBONATED BEVERAGES, POLYESTER AND SAPONIFIED ETHYLENE-VINYL ACETATE | KURARAY CO., LTD. (JP) | 1988-09-27 | — | — | US | disclosed |
| EP-0165383-A2 | Resinous composition | KURARAY CO., LTD. (JP) | 1985-12-27 | — | — | EP | disclosed |
| US-4284671-A | BLENDS WITH ETHYLENE-VINYL ALCOHOL COPOLYMER; FOR PACKAGING | CLOPAY CORPORATION (US) | 1981-08-18 | — | — | US | disclosed |
| EP-0019438-A1 | Polyester compositions for gas and moisture barrier materials, barrier materials formed from said compositions and a container formed from a layer of said barrier material | CLOPAY CORPORATION (US) | 1980-11-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140213818-A1 | PROCESS FOR THE PREPARATION OF BETA-SANTALOL | ACSL3, ACSL1, CSNK1A1L | TSHR 2364/4885DAO 507/4885NAPRT 1604/4885 |
| US-20260146118-A1 | ACETALIZATION PRODUCT OF ETHYLENEVINYL ALCOHOL COPOLYMER, COMPOSITION CONTAINING SAID ACETALIZATION PRODUCT, AND BARRIER MATERIAL | ADH1A, GK, ADH1C | TSHR 2692/4885DAO 3268/4885NAPRT 4760/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.