Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.74 |
| ▸ | DAO | P14920 | 1/20 | 0.74 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.74 |
| ▸ | CES2 | O00748 | 3/20 | 0.61 |
| ▸ | CES1 | P23141 | 3/20 | 0.61 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.61 |
| ▸ | AKT1 | P31749 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | KMO | O15229 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL9659726 | 0.90 | TSHR (0.67) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL27616171 | 0.90 | TSHR (0.74) | TSHRDAONAPRTCES2CES1 | |
| Terephthalic Acid SCHEMBL332989 | 0.89 | TSHR (0.71) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL28553415 | 0.87 | TSHR (0.70) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL4158962 | 0.87 | TSHR (0.70) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL9644655 | 0.87 | TSHR (0.70) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL8968112 | 0.87 | TSHR (0.70) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL30978335 | 0.87 | TSHR (0.70) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL28775769 | 0.87 | TSHR (0.70) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL10493461 | 0.87 | TSHR (0.70) | TSHRDAONAPRTCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116856096-A | Antistatic compact spinning grid ring and preparation process thereof | 无锡市兰盾纺织器材有限公司 | 2023-10-10 | — | — | CN | claimed |
| US-7875662-B2 | Reacting PbCO3 with acrylic acid monomer to form a salt, mixing with a crosslinker (ethylene glycol, dimethacrylate) and an initiator in a solvent; solution polymerizing styrene to form polystyrene beads, absorbing dibutyl phthalate, forming metal ion imprinted polymer on seed, removing metal ions | SUNGKYUNKWAN UNIVERSITY FOUNDATION FOR CORPORATE COLLABORATION (KR) | 2011-01-25 | — | — | US | claimed |
| US-20080221248-A1 | METHOD FOR PREPARING SURFACE-IMPRINTED POLYMER MICROSPHERES IN THE FORM OF CORE-SHELL FOR SELECTIVE SEPARATION OF HEAVY METAL IONS | SUNGKYUNKWAN UNIVERSITY FOUNDATION FOR CORPORATE COLLABORATION (KR) | 2008-09-11 | — | — | US | claimed |
| US-20070191551-A1 | Selective separation of heavy metal ion using metal ion imprinted polymer (MMIP) | SUNGKYUNKWAN UNIVERSITY FOUNDATION FOR CORPORATE COLLABORATION (KR) | 2007-08-16 | — | — | US | claimed |
| CN-116856096-B | Antistatic compact spinning grid ring and preparation process thereof | 无锡市兰盾纺织器材有限公司 | 2025-10-28 | — | — | CN | disclosed |
| WO-2024057235-A1 | MULTI-SURFACE COATING COMPOSITION | CONSORCIO COMEX, S.A. DE C.V. (MX) | 2024-03-21 | — | — | WO | disclosed |
| WO-2024057233-A1 | MULTI-FUNCTIONAL COATING COMPOSITION | CONSORCIO COMEX, S.A. DE C.V. (MX) | 2024-03-21 | — | — | WO | disclosed |
| CN-116856096-A | Antistatic compact spinning grid ring and preparation process thereof | 无锡市兰盾纺织器材有限公司 | 2023-10-10 | — | — | CN | disclosed |
| CN-116856096-A | Antistatic compact spinning grid ring and preparation process thereof | 无锡市兰盾纺织器材有限公司 | 2023-10-10 | — | — | CN | disclosed |
| EP-3420042-B1 | THERMOSETTING COATING COMPOSITIONS | EASTMAN CHEM CO (US) | 2022-06-29 | — | — | EP | disclosed |
| CN-108699383-B | Thermosetting coating composition | 伊士曼化工公司 | 2021-02-12 | — | — | CN | disclosed |
| CN-110892028-A | Aqueous inkjet ink and method for producing printed matter | 世联株式会社 | 2020-03-17 | — | — | CN | disclosed |
| US-4778862-A | Fluorine and acrylic modified silicone resins | THE GLIDDEN COMPANY (US) | 1988-10-18 | — | — | US | disclosed |
| US-4766177-A | THERMOSETTING ACRYLIC POLYMERS AND AN ADHESIVE-PROMOTER POLYESTERURETHANE | THE GLIDDEN COMPANY (US) | 1988-08-23 | — | — | US | disclosed |
| EP-0275051-A2 | Acrylic modified silicone resins | THE GLIDDEN COMPANY (US) | 1988-07-20 | — | — | EP | disclosed |
| US-4751267-A | BLEND OF ACRYLIC POLYMER, POLYESTER AND AMINE CROSSLINKING RESIN-PROTECTIVE COATINGS | THE GLIDDEN COMPANY (US) | 1988-06-14 | — | — | US | disclosed |
| EP-0256369-A2 | Glycidyl acrylic powder coatings | THE GLIDDEN COMPANY (US) | 1988-02-24 | — | — | EP | disclosed |
| US-4716200-A | BLENDS HAVING CROSSLINKING AGENT | THE GLIDDEN COMPANY (US) | 1987-12-29 | — | — | US | disclosed |
| EP-0237285-A2 | High solid polymer composition | THE GLIDDEN COMPANY (US) | 1987-09-16 | — | — | EP | disclosed |
| US-4487860-A | POLYELECTROLYTES, POLYPHOSPHATES, ACRYLIC COPOLMERS, IONIZING AGENTS | SCM CORPORATION (US) | 1984-12-11 | — | — | US | disclosed |