SCHEMBL8968190

SCHEMBL8968190

O=C(O)c1cc(C(=O)O)cc(S(=O)(=O)NS(=O)(=O)Cc2ccccc2)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.50
CYP1A2 P05177 1/20 0.50
TSHR P16473 1/20 0.50
CA1 P00915 2/20 0.49
CA2 P00918 2/20 0.49
MMP1 P03956 1/20 0.49
MMP2 P08253 1/20 0.49
MMP9 P14780 1/20 0.49
MMP8 P22894 1/20 0.49
MMP13 P45452 1/20 0.49
AKR1C3 P42330 1/20 0.48
HPGD P15428 1/20 0.48
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
ACLY P53396 1/20 0.44
LCK P06239 1/20 0.43
FYN P06241 1/20 0.43
P4HTM Q9NXG6 1/20 0.43
GAA P10253 1/20 0.42
S1PR3 Q99500 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24360900 0.80 CA1 (0.57) CA1CA2MMP1MMP2MMP9
SCHEMBL9818366 0.78 HPGD (0.61) HSD17B10TSHRCA1CA2MMP1
SCHEMBL6492175 0.74 CA1 (0.68) CA1CA2MMP1MMP2MMP9
SCHEMBL7424336 0.72 POLB (0.50) TSHRCA1CA2HPGDMEN1
SCHEMBL28678247 0.72 HDAC2 (0.60) CYP1A2CA1CA2AKR1C3MEN1
SCHEMBL8968181 0.70 CYP1A2 (0.54) CYP1A2CA1CA2MMP1MMP2
SCHEMBL1650346 0.70 HPGD (0.77) HSD17B10TSHRCA1CA2MMP1
SCHEMBL15056487 0.70 AKR1C3 (0.51) HSD17B10CYP1A2TSHRCA1CA2
SCHEMBL15821248 0.70 TSHR (0.68) HSD17B10TSHRCA1CA2AKR1C3
SCHEMBL6797222 0.70 HPGD (0.58) HSD17B10AKR1C3HPGDKMT2AACLY

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5571457-A SULFONATED POLYCAPROLACTONE ARYLDICARBOXYLATE, FERRIC HALIDE COMPLEX EASTMAN KODAK COMPANY (US) 1996-11-05 US disclosed
EP-0700055-A2 Biasable transfer members having extended electrical life EASTMAN KODAK COMPANY (US) 1996-03-06 EP disclosed