Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.68 |
| ▸ | CA2 | P00918 | 2/20 | 0.68 |
| ▸ | MMP1 | P03956 | 1/20 | 0.68 |
| ▸ | MMP2 | P08253 | 1/20 | 0.68 |
| ▸ | MMP9 | P14780 | 1/20 | 0.68 |
| ▸ | MMP8 | P22894 | 1/20 | 0.68 |
| ▸ | MMP13 | P45452 | 1/20 | 0.68 |
| ▸ | FAAH | O00519 | 1/20 | 0.56 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.56 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.56 |
| ▸ | ELANE | P08246 | 1/20 | 0.56 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.56 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.56 |
| ▸ | CA5A | P35218 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | PGR | P06401 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | AR | P10275 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24361302 | 0.87 | CA1 (0.59) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL24360900 | 0.85 | CA1 (0.57) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL9006011 | 0.83 | CA1 (0.65) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL21763639 | 0.83 | CA1 (0.65) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL465380 | 0.83 | CA1 (0.65) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL4301369 | 0.82 | CA1 (0.53) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL10656290 | 0.81 | CA1 (1.00) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL12068211 | 0.81 | CA1 (0.63) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL4678467 | 0.81 | CA1 (0.63) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL13325 | 0.81 | CA1 (0.63) | CA1CA2MMP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040058903-A1 | Benzamide compounds as apo b secretion inhibitors | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-03-25 | — | — | US | claimed |
| US-20050038035-A1 | Heterocyclic amide compounds as apolipoprotein b inhibitors | DAISO CO., LTD. (JP) | 2005-02-17 | — | — | US | disclosed |
| US-20040058903-A1 | Benzamide compounds as apo b secretion inhibitors | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-03-25 | — | — | US | disclosed |
| EP-1198505-B1 | CARBONATE POLYMER COMPOSITIONS STABILIZED AGAINST DISCOLORATION AND PHYSICAL PROPERTY DETERIORATION DURING STERILIZATION BY IONIZING RADIATION | DOW GLOBAL TECHNOLOGIES INC (US) | 2004-01-07 | — | — | EP | disclosed |
| EP-1198505-A1 | CARBONATE POLYMER COMPOSITIONS STABILIZED AGAINST DISCOLORATION AND PHYSICAL PROPERTY DETERIORATION DURING STERILIZATION BY IONIZING RADIATION | THE DOW CHEMICAL COMPANY (US) | 2002-04-24 | — | — | EP | disclosed |
| US-6166116-A | Carbonate polymer compositions stabilized against discoloration and physical property deterioration during sterilization by ionizing radiation | THE DOW CHEMICAL COMPANY (US) | 2000-12-26 | — | — | US | disclosed |
| WO-2000075223-A1 | CARBONATE POLYMER COMPOSITIONS STABILIZED AGAINST DISCOLORATION AND PHYSICAL PROPERTY DETERIORATION DURING STERILIZATION BY IONIZING RADIATION | THE DOW CHEMICAL COMPANY (US) | 2000-12-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040058903-A1 | Benzamide compounds as apo b secretion inhibitors | APOB, APOL1, SCARB1 | CA1 4466/4885CA2 3850/4885MMP1 968/4885 |
| US-20050038035-A1 | Heterocyclic amide compounds as apolipoprotein b inhibitors | APOB, APOL1, CTRB2 | CA1 2761/4885CA2 1990/4885MMP1 779/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.