Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RELA | Q04206 | 5/20 | 0.76 |
| ▸ | ABL1 | P00519 | 2/20 | 0.73 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.73 |
| ▸ | BCR | P11274 | 2/20 | 0.73 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.65 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.63 |
| ▸ | NQO2 | P16083 | 2/20 | 0.59 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.58 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.58 |
| ▸ | MAOB | P27338 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Hydroxy-4'-Methoxystilbene SCHEMBL8968277 | 1.00 | RELA (0.76) | RELAABL1ABCB1BCRNFE2L2 | |
| SCHEMBL631997 | 0.87 | TRPA1 (0.76) | RELAABL1ABCB1BCRNFE2L2 | |
| SCHEMBL631996 | 0.87 | TRPA1 (0.76) | RELAABL1ABCB1BCRNFE2L2 | |
| SCHEMBL5492969 | 0.86 | RELA (1.00) | RELAABL1ABCB1BCRNFE2L2 | |
| SCHEMBL5492964 | 0.86 | RELA (1.00) | RELAABL1ABCB1BCRNFE2L2 | |
| SCHEMBL28356927 | 0.84 | F3 (0.71) | RELAABL1ABCB1BCRNFE2L2 | |
| SCHEMBL13926062 | 0.82 | RELA (0.74) | RELAABL1ABCB1BCRNFE2L2 | |
| SCHEMBL21095052 | 0.81 | ABL1 (0.77) | RELAABL1ABCB1BCRNFE2L2 | |
| SCHEMBL9419855 | 0.81 | ABL1 (0.77) | RELAABL1ABCB1BCRNFE2L2 | |
| SCHEMBL9419858 | 0.81 | ABL1 (0.77) | RELAABL1ABCB1BCRNFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5314693-A | Hydroxystilbene compounds | KIORITZ CORPORATION (JP) | 1994-05-24 | — | — | US | claimed |
| CN-111848560-A | Preparation method of benzofuran derivative | 中国科学院成都生物研究所 | 2020-10-30 | — | — | CN | disclosed |
| EP-2875359-A2 | COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING METABOLIC SYNDROME DISORDERS | Charles R Drew University of Medicine and Science (US) | 2015-05-27 | — | — | EP | disclosed |
| WO-2013149258-A2 | COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING METABOLIC SYNDROME DISORDERS | Charles Drew University of Medicine and Science (US) | 2013-10-03 | — | — | WO | disclosed |
| US-5530030-A | CHLORINATED HYDROXYSTILBENES | KIORITZ CORPORATIN (JP) | 1996-06-25 | — | — | US | disclosed |
| US-5314693-A | Hydroxystilbene compounds | KIORITZ CORPORATION (JP) | 1994-05-24 | — | — | US | disclosed |
| EP-0409070-A2 | Mesogenic cyanite functional maleimides and thermosets thereof | THE DOW CHEMICAL COMPANY (US) | 1991-01-23 | — | — | EP | disclosed |