Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 2/20 | 0.43 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | USP7 | Q93009 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.41 |
| ▸ | TUBB | P07437 | 2/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.41 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.41 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.41 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.41 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8969565 | 0.79 | HTR6 (0.43) | HTR6TLR9NPC1RAB9AUSP7 | |
| SCHEMBL8968935 | 0.77 | HTR6 (0.45) | HTR6NPC1RAB9AMEN1KMT2A | |
| SCHEMBL8969408 | 0.72 | ALDH1A1 (0.41) | HTR6NPC1RAB9AMEN1KMT2A | |
| SCHEMBL8969177 | 0.71 | KDM4E (0.50) | HTR6NPC1RAB9AMEN1KMT2A | |
| SCHEMBL8968968 | 0.71 | KDM4E (0.53) | HTR6NPC1RAB9AMEN1KMT2A | |
| SCHEMBL8968970 | 0.70 | KDM4E (0.48) | HTR6NPC1RAB9AMEN1KMT2A | |
| SCHEMBL8969667 | 0.70 | KDM4E (0.41) | HTR6NPC1RAB9AUSP7MEN1 | |
| SCHEMBL8969236 | 0.70 | KDM4E (0.41) | HTR6NPC1RAB9AMEN1KMT2A | |
| SCHEMBL8968887 | 0.70 | ALDH1A1 (0.41) | HTR6NPC1RAB9AMEN1KMT2A | |
| SCHEMBL8969928 | 0.69 | ALDH1A1 (0.40) | HTR6NPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |