Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 8/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | FPR2 | P25090 | 2/20 | 0.61 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.61 |
| ▸ | MTOR | P42345 | 1/20 | 0.61 |
| ▸ | MYLK | Q15746 | 1/20 | 0.61 |
| ▸ | NSD2 | O96028 | 7/20 | 0.61 |
| ▸ | TP53 | P04637 | 6/20 | 0.60 |
| ▸ | THPO | P40225 | 4/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.60 |
| ▸ | PMP22 | Q01453 | 3/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.60 |
| ▸ | APEX1 | P27695 | 1/20 | 0.60 |
| ▸ | BLM | P54132 | 1/20 | 0.60 |
| ▸ | SCN1A | P35498 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8488159 | 0.91 | CYP3A4 (0.59) | CYP3A4CYP1A2CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL11573784 | 0.86 | NSD2 (0.59) | CYP3A4CYP1A2CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL19603056 | 0.84 | CYP3A4 (0.81) | CYP3A4CYP1A2CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL11686439 | 0.83 | NSD2 (0.86) | CYP3A4CYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL9050527 | 0.82 | NSD2 (0.56) | CYP2C9CYP2C19NSD2NPSR1TSHR | |
| SCHEMBL1366996 | 0.79 | NSD2 (0.55) | NSD2 | |
| SCHEMBL8864869 | 0.79 | NSD2 (0.54) | NSD2 | |
| SCHEMBL4263470 | 0.79 | CYP3A4 (0.78) | CYP3A4CYP1A2CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL9894851 | 0.79 | NSD2 (0.52) | CYP3A4CYP1A2CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL3354585 | 0.78 | NSD2 (0.54) | CYP1A2CYP2C9CYP2D6KDM4ENSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2003448-A | — | — | None | — | — | JP | disclosed |
| US-20160375143-A1 | MIKTO-ARM BRANCHED POLYMERS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2016-12-29 | — | — | US | disclosed |
| EP-3074440-A1 | MIKTO-ARM BRANCHED POLYMERS | Commonwealth Scientific & Industrial Research Organisation ( C.S.I.R.O. ) (AU) | 2016-10-05 | — | — | EP | disclosed |
| WO-2015077831-A1 | MIKTO-ARM BRANCHED POLYMERS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2015-06-04 | — | — | WO | disclosed |
| EP-0451824-B1 | Chelating compounds and their use | NIHON MEDIPHYSICS CO LTD (JP) | 1996-02-14 | — | — | EP | disclosed |
| US-5196576-A | Medical imaging of liver tissue | NIHON MEDI-PHYSICS CO., LTD. (JP) | 1993-03-23 | — | — | US | disclosed |
| US-5138039-A | Diagnosis, therapy | NIHON MEDI-PHYSICS CO., LTD (JP) | 1992-08-11 | — | — | US | disclosed |
| JP-H023448-A | FLUORESCENT ACRYLAMIDE COMPOUND | SEIKO INSTR INC | 1990-01-09 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160375143-A1 | MIKTO-ARM BRANCHED POLYMERS | MACO1, PCNA, IPO7 | CYP3A4 3083/4885CYP1A2 4493/4885CYP2C9 4440/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.