SCHEMBL3354585

SCHEMBL3354585

C=CCNS(=O)(=O)c1ccc(N)c2ccccc12

nearest known ligand 0.54

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
NSD2 O96028 16/20 0.54
KDM4E B2RXH2 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2D6 P10635 1/20 0.44
CYP2C9 P11712 1/20 0.44
CASP1 P29466 1/20 0.44
CASP7 P55210 1/20 0.44
TTR P02766 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1366996 0.86 NSD2 (0.55) NSD2TTR
SCHEMBL6443974 0.81 CA9 (0.47) NSD2KDM4ECYP1A2CYP2D6CYP2C9
SCHEMBL7906849 0.78 KDM4E (0.59) KDM4ECYP1A2CYP2D6CYP2C9CASP1
SCHEMBL8968288 0.78 CYP3A4 (0.61) NSD2KDM4ECYP1A2CYP2D6CYP2C9
SCHEMBL11573784 0.77 NSD2 (0.59) NSD2KDM4ECYP1A2CYP2D6CYP2C9
SCHEMBL8864869 0.77 NSD2 (0.54) NSD2TTR
SCHEMBL9050527 0.77 NSD2 (0.56) NSD2CYP2C9
SCHEMBL386440 0.76 NSD2 (0.57) NSD2
SCHEMBL1316261 0.76 NSD2 (0.54) NSD2KDM4ECYP1A2CYP2D6CYP2C9
SCHEMBL8488159 0.76 CYP3A4 (0.59) NSD2KDM4ECYP1A2CYP2D6CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4326008-A CROSSLINKED ACRYLIC POLYMERS CONTAINING A FLUORESCENT COMONOMER CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1982-04-20 US claimed
US-8410225-B2 Fluorescent nanoparticles BRIDGESTONE CORPORATION (JP) 2013-04-02 US disclosed
US-20100016512-A1 Fluorescent Nanoparticles BRIDGESTONE CORPORATION (JP) 2010-01-21 US disclosed
US-7597959-B2 Core-shell fluorescent nanoparticles BRIDGESTONE CORPORATION (JP) 2009-10-06 US disclosed
WO-2008079276-A1 FLUORESCENT NANOPARTICLES BRIDGESTONE CORPORATION (JP) 2008-07-03 WO disclosed
US-20080145660-A1 shell-core copolymers having pyrene dye portion located in any locations; comonomers consisting of Cinnamyl-O CH2-pyrene Fluorescent Monomer, t-Butylstyrene, Butadiene; use of fluorescent labels in medicine and biology; non-carcinogenic BRIDGESTONE CORPORATION (JP) 2008-06-19 US disclosed
US-5723218-A Dipyrrometheneboron difluoride labeled flourescent microparticles MOLECULAR PROBES, INC. (US) 1998-03-03 US disclosed
US-4873102-A SWELLING POROUS POLYMER IN AQUEOUS SOLUTION OF STRONG ACID SALT OF IRON, COBALT, OR NICKEL, AND BASIFICATION CALIFORNIA INSTITUTE OF TECHNOLOGY 1989-10-10 US disclosed
US-4707523-A Magnetic particles CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1987-11-17 US disclosed
US-4665020-A Flow cytometer measurement of binding assays UNITED STATES DEPARTMENT OF ENERGY (US) 1987-05-12 US disclosed
US-4326008-A CROSSLINKED ACRYLIC POLYMERS CONTAINING A FLUORESCENT COMONOMER CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1982-04-20 US disclosed
US-4326008-A CROSSLINKED ACRYLIC POLYMERS CONTAINING A FLUORESCENT COMONOMER CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1982-04-20 US disclosed