SCHEMBL8968405

SCHEMBL8968405

[c]1ccccc1Oc1cccc(Oc2[c]cccc2)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.39
MAPT P10636 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
GAA P10253 2/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
MITF O75030 1/20 0.39
GFER P55789 1/20 0.39
NLRP1 Q9C000 1/20 0.39
NOD2 Q9HC29 1/20 0.39
MAOB P27338 1/20 0.38
LMNA P02545 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
LTA4H P09960 1/20 0.35
TSHR P16473 1/20 0.35
AKR1C3 P42330 1/20 0.34
FURIN P09958 2/20 0.33
F2 P00734 1/20 0.33
F10 P00742 1/20 0.33
POLB P06746 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5998888 0.94 MAOB (0.47) ALDH1A1MAPTSMN1; SMN2GAAMEN1
SCHEMBL5537810 0.91 SMN1; SMN2 (0.47) ALDH1A1MAPTSMN1; SMN2MEN1KMT2A
SCHEMBL28263216 0.87 FFAR1 (0.39) MAOBLTA4H
SCHEMBL1532130 0.87 MAOB (0.42) KMT2AMAOBRAB9A
SCHEMBL4735399 0.87 MAOB (0.58) ALDH1A1MAPTSMN1; SMN2GAAMEN1
SCHEMBL5542251 0.87 ALDH1A1 (0.49) ALDH1A1MAPTGAAMEN1KMT2A
SCHEMBL1532138 0.87 SLC6A4 (0.39) ALDH1A1MAPTF10POLBHSP90AA1
SCHEMBL1532086 0.87 CYP1A2 (0.43) MAPTSMN1; SMN2LMNA
SCHEMBL1929679 0.87 MAOB (0.32) MAOBAKR1C3
SCHEMBL76698 0.86 LTA4H (0.50) MAPTGAAKMT2AMAOBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0699216-A1 MELT PROCESSABLE POLYESTERS AND POLY(IMIDE-ESTERS) E.I. DU PONT DE NEMOURS AND COMPANY (US) 1996-03-06 EP disclosed
WO-1994028052-A1 MELT PROCESSABLE POLYESTERS AND POLY(IMIDE-ESTERS) E.I. DU PONT DE NEMOURS AND COMPANY (US) 1994-12-08 WO disclosed
US-5288835-A 4,4*-bis(hydroxyphenoxy)biphenyl as one of the monomer E. I. DU PONT DE NEMOURS AND COMPANY (US) 1994-02-22 US disclosed