Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | STAT6 | P42226 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8969076 | 0.82 | ACHE (0.63) | ACHEALDH1A1SMN1; SMN2TP53MEN1 | |
| SCHEMBL8969409 | 0.79 | ACHE (0.63) | ACHEALDH1A1SMN1; SMN2GAAMEN1 | |
| SCHEMBL8968607 | 0.79 | ACHE (0.71) | ACHEALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8969040 | 0.78 | ACHE (0.46) | ACHEALDH1A1SMN1; SMN2TP53MAPT | |
| SCHEMBL3899169 | 0.78 | SMN1; SMN2 (0.60) | ACHEALDH1A1SMN1; SMN2RXFP1TP53 | |
| SCHEMBL8969258 | 0.77 | ACHE (0.60) | ACHEALDH1A1SMN1; SMN2BCHEMEN1 | |
| SCHEMBL8969447 | 0.77 | ACHE (0.68) | ACHEALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8968338 | 0.77 | SMN1; SMN2 (0.71) | ACHEALDH1A1SMN1; SMN2TP53APP | |
| SCHEMBL8969117 | 0.77 | ACHE (0.71) | ACHEALDH1A1SMN1; SMN2RXFP1TP53 | |
| SCHEMBL8969913 | 0.75 | ACHE (0.49) | ACHEALDH1A1SMN1; SMN2RXFP1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |