Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 6/20 | 0.44 |
| ▸ | TP53 | P04637 | 8/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8968609 | 0.78 | ACHE (0.54) | ACHELMNATP53MAPTSMN1; SMN2 | |
| SCHEMBL8969040 | 0.78 | ACHE (0.46) | ACHELMNATP53MAPTGAA | |
| SCHEMBL8968476 | 0.75 | ACHE (0.59) | ACHETP53MAPTGAASMN1; SMN2 | |
| SCHEMBL8968510 | 0.74 | ACHE (0.60) | ACHELMNATP53MAPTSMN1; SMN2 | |
| SCHEMBL8969799 | 0.74 | ACHE (0.53) | ACHELMNATP53MAPTGAA | |
| SCHEMBL8968464 | 0.74 | ACHE (0.50) | ACHELMNATP53MAPTGAA | |
| SCHEMBL8968416 | 0.72 | ACHE (0.48) | ACHELMNAMAPTGAASMN1; SMN2 | |
| SCHEMBL8969210 | 0.72 | ACHE (0.58) | ACHELMNATP53MAPTSMN1; SMN2 | |
| SCHEMBL8968236 | 0.72 | ACHE (0.51) | ACHELMNATP53MAPTGAA | |
| SCHEMBL8970389 | 0.71 | ACHE (0.50) | ACHELMNATP53MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |