Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 4/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.41 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8968581 | 0.99 | ACHE (0.60) | ACHEALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8969364 | 0.89 | ACHE (0.69) | ACHEALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8969432 | 0.87 | ACHE (0.71) | ACHEALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8969679 | 0.83 | ACHE (0.78) | ACHEALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8968576 | 0.83 | SMN1; SMN2 (0.69) | ACHEALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8969258 | 0.82 | ACHE (0.60) | ACHEALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8969470 | 0.82 | ACHE (0.60) | ACHEALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8968881 | 0.82 | ACHE (0.80) | ACHEALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8968338 | 0.82 | SMN1; SMN2 (0.71) | ACHEALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8969409 | 0.81 | ACHE (0.63) | ACHEALDH1A1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |