Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.71 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8969364 | 0.99 | ACHE (0.69) | ACHEMEN1KMT2AHDAC6ALDH1A1 | |
| SCHEMBL8968581 | 0.89 | ACHE (0.60) | ACHEMEN1KMT2AHDAC6ALDH1A1 | |
| SCHEMBL8968524 | 0.87 | ACHE (0.58) | ACHEMEN1KMT2AHDAC6ALDH1A1 | |
| SCHEMBL8968366 | 0.83 | ACHE (1.00) | ACHEMEN1KMT2AHDAC6ALDH1A1 | |
| SCHEMBL8969117 | 0.83 | ACHE (0.71) | ACHEMEN1KMT2AHDAC6ALDH1A1 | |
| SCHEMBL8969578 | 0.83 | ACHE (0.71) | ACHEMEN1KMT2AHDAC6ALDH1A1 | |
| SCHEMBL2050608 | 0.83 | MEN1 (0.66) | ACHEMEN1KMT2AHDAC6ALDH1A1 | |
| SCHEMBL8969409 | 0.83 | ACHE (0.63) | ACHEMEN1KMT2AHDAC6ALDH1A1 | |
| SCHEMBL6920428 | 0.82 | MEN1 (0.63) | ACHEMEN1KMT2AHDAC6ALDH1A1 | |
| SCHEMBL8968638 | 0.82 | ACHE (0.69) | ACHEMEN1KMT2AHDAC6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |