Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 6/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KLK7 | P49862 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8969433 | 0.87 | ACHE (0.38) | ACHEPOLBL3MBTL1 | |
| SCHEMBL8968233 | 0.82 | ACHE (0.57) | ACHEL3MBTL1KLK7DRD2DRD4 | |
| SCHEMBL8969421 | 0.81 | ACHE (0.63) | ACHEL3MBTL1KLK7BCHEMEN1 | |
| Hydrochloric Acid SCHEMBL8969536 | 0.81 | ACHE (0.56) | ACHEKLK7DRD2DRD4DRD3 | |
| SCHEMBL29869033 | 0.80 | ACHE (0.66) | ACHEL3MBTL1KLK7BCHEMEN1 | |
| SCHEMBL4448665 | 0.80 | ACHE (0.66) | ACHEL3MBTL1KLK7BCHEMEN1 | |
| Hydrochloric Acid SCHEMBL8968390 | 0.79 | ACHE (0.64) | ACHEL3MBTL1KLK7BCHEMEN1 | |
| SCHEMBL8969066 | 0.78 | ACHE (0.67) | ACHEDRD2DRD4DRD3BCHE | |
| SCHEMBL8969485 | 0.78 | ACHE (0.43) | ACHEKLK7DRD2DRD4DRD3 | |
| SCHEMBL8969455 | 0.78 | ACHE (0.43) | ACHEDRD2DRD4DRD3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |