Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8968631 | 0.87 | ACHE (0.38) | ACHEMAPTRAB9ASMN1; SMN2MAPK1 | |
| SCHEMBL8968233 | 0.82 | ACHE (0.57) | ACHERAB9ASMN1; SMN2NPC1KMT2A | |
| SCHEMBL8969421 | 0.81 | ACHE (0.63) | ACHERAB9ASMN1; SMN2NPC1KMT2A | |
| Hydrochloric Acid SCHEMBL8969536 | 0.81 | ACHE (0.56) | ACHEKMT2AMEN1DRD2DRD4 | |
| SCHEMBL4448665 | 0.80 | ACHE (0.66) | ACHERAB9ASMN1; SMN2NPC1KMT2A | |
| SCHEMBL29869033 | 0.80 | ACHE (0.66) | ACHERAB9ASMN1; SMN2NPC1KMT2A | |
| Hydrochloric Acid SCHEMBL8968390 | 0.79 | ACHE (0.64) | ACHERAB9ASMN1; SMN2NPC1KMT2A | |
| SCHEMBL8969485 | 0.78 | ACHE (0.43) | ACHEKMT2AMEN1DRD2DRD4 | |
| SCHEMBL8968698 | 0.78 | ACHE (0.43) | ACHEKMT2AMEN1DRD2DRD4 | |
| SCHEMBL8970011 | 0.76 | ACHE (0.41) | ACHECNR2DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |