Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALPG | P10696 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | STAT1 | P42224 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8968470 | 0.86 | ACHE (0.64) | ACHELMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8968724 | 0.86 | ACHE (0.50) | ACHELMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8969554 | 0.85 | ACHE (0.61) | ACHELMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8968731 | 0.81 | ACHE (0.56) | ACHELMNANPC1RAB9AALDH1A1 | |
| SCHEMBL8968279 | 0.78 | ACHE (0.50) | ACHELMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8968622 | 0.77 | ACHE (0.51) | ACHELMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8970467 | 0.77 | ACHE (0.48) | ACHELMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8968366 | 0.76 | ACHE (1.00) | ACHELMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8969076 | 0.75 | ACHE (0.63) | ACHELMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8968733 | 0.74 | ACHE (0.97) | ACHELMNANPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |