Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | STAT1 | P42224 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8969554 | 0.99 | ACHE (0.61) | ACHERAB9ANPC1LMNAPOLB | |
| SCHEMBL8968731 | 0.94 | ACHE (0.56) | ACHERAB9ANPC1LMNAPOLB | |
| SCHEMBL8968996 | 0.86 | ACHE (0.61) | ACHERAB9ANPC1LMNAPOLB | |
| SCHEMBL8968447 | 0.83 | POLB (0.58) | ACHERAB9ANPC1LMNAPOLB | |
| SCHEMBL8968425 | 0.83 | MEN1 (0.55) | ACHERAB9ANPC1LMNAPOLB | |
| SCHEMBL8968557 | 0.82 | POLB (0.56) | ACHERAB9ANPC1LMNAPOLB | |
| SCHEMBL8968614 | 0.78 | ACHE (0.56) | ACHERAB9ANPC1LMNAPOLB | |
| SCHEMBL8968366 | 0.78 | ACHE (1.00) | ACHERAB9ANPC1LMNAPOLB | |
| SCHEMBL8968656 | 0.78 | ACHE (0.60) | ACHERAB9ANPC1LMNAPOLB | |
| SCHEMBL8969257 | 0.77 | POLB (0.50) | ACHERAB9ANPC1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |