Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR5A1 | Q13285 | 1/20 | 0.61 |
| ▸ | LTA4H | P09960 | 4/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.53 |
| ▸ | RARB | P10826 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | THRA | P10827 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 2/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1702948 | 0.92 | LTA4H (0.55) | NR5A1LTA4HTP53TSHRGAA | |
| SCHEMBL482139 | 0.91 | LTA4H (0.64) | NR5A1LTA4HTP53TSHRPLA2G4B | |
| SCHEMBL482308 | 0.91 | LTA4H (0.64) | NR5A1LTA4HTP53TSHRPLA2G4B | |
| SCHEMBL3407783 | 0.91 | NR5A1 (0.56) | NR5A1LTA4HTP53TSHRPLA2G4B | |
| SCHEMBL4619331 | 0.91 | NR5A1 (0.56) | NR5A1LTA4HTP53TSHRPLA2G4B | |
| SCHEMBL9333524 | 0.91 | LTA4H (0.64) | NR5A1LTA4HTP53TSHRPLA2G4B | |
| SCHEMBL2437395 | 0.91 | LTA4H (0.64) | NR5A1LTA4HTP53TSHRPLA2G4B | |
| SCHEMBL4619678 | 0.91 | NR5A1 (0.56) | NR5A1LTA4HTP53TSHRPLA2G4B | |
| SCHEMBL482305 | 0.91 | LTA4H (0.64) | NR5A1LTA4HTP53TSHRPLA2G4B | |
| Ethane SCHEMBL2441158 | 0.90 | LTA4H (0.62) | NR5A1LTA4HTP53TSHRPLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0644888-B1 | SULPHONIUM SALTS AND PROCESS FOR PRODUCING THEM | WACKER CHEMIE GMBH (DE) | 1996-03-13 | — | — | EP | disclosed |
| US-5466845-A | Contain silane groups, photoinitiators | WACKER-CHEMIE GMBH (DE) | 1995-11-14 | — | — | US | disclosed |
| EP-0644888-A1 | SULPHONIUM SALTS AND PROCESS FOR PRODUCING THEM. | WACKER CHEMIE GMBH (DE) | 1995-03-29 | — | — | EP | disclosed |
| WO-1993025559-A1 | SULPHONIUM SALTS AND PROCESS FOR PRODUCING THEM | WACKER-CHEMIE GMBH (DE) | 1993-12-23 | — | — | WO | disclosed |