SCHEMBL8969152

SCHEMBL8969152

O=C(O)Cc1ccccc1Oc1cccc(Oc2ccccc2CC(=O)O)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CAMK2A Q9UQM7 3/20 0.62
CXCL8 P10145 2/20 0.61
CHRM1 P11229 1/20 0.57
PLAU P00749 2/20 0.51
AKR1B1 P15121 1/20 0.48
PTGDR2 Q9Y5Y4 1/20 0.48
CFD P00746 1/20 0.48
PLG P00747 1/20 0.48
F11 P03951 1/20 0.48
KLKB1 P03952 1/20 0.48
F7 P08709 1/20 0.48
TPSB2 P20231 1/20 0.48
TDP1 Q9NUW8 1/20 0.47
SLC1A5 Q15758 1/20 0.47
FFAR1 O14842 1/20 0.47
HRH1 P35367 1/20 0.46
PTGER1 P34995 1/20 0.46
PTGER4 P35408 1/20 0.46
PTGER3 P43115 1/20 0.46
PTGER2 P43116 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9288801 0.97 CAMK2A (0.63) CAMK2ACXCL8CHRM1PLAUFFAR1
SCHEMBL9152146 0.92 SLC1A5 (0.57) CAMK2ACXCL8CHRM1PLAUPTGDR2
SCHEMBL838629 0.91 CAMK2A (0.68) CAMK2ACXCL8CHRM1AKR1B1PTGDR2
SCHEMBL9148385 0.91 SLC1A5 (0.56) CAMK2ACXCL8CHRM1PLAUPTGDR2
SCHEMBL9420375 0.91 CAMK2A (0.68) CAMK2ACXCL8CHRM1PLAUAKR1B1
Hydrogen Sulfide SCHEMBL28780977 0.89 CAMK2A (0.66) CAMK2ACXCL8CHRM1AKR1B1PTGDR2
SCHEMBL30748257 0.89 CXCL8 (0.61) CAMK2ACXCL8CHRM1PLAUPTGDR2
SCHEMBL11447649 0.89 CXCL8 (0.61) CAMK2ACXCL8CHRM1PLAUPTGDR2
SCHEMBL22977723 0.89 CHRM1 (0.66) CAMK2ACXCL8CHRM1PLAUPTGDR2
SCHEMBL10515333 0.88 CAMK2A (0.54) CAMK2ACXCL8CHRM1PLAUTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0699216-A1 MELT PROCESSABLE POLYESTERS AND POLY(IMIDE-ESTERS) E.I. DU PONT DE NEMOURS AND COMPANY (US) 1996-03-06 EP disclosed
WO-1994028052-A1 MELT PROCESSABLE POLYESTERS AND POLY(IMIDE-ESTERS) E.I. DU PONT DE NEMOURS AND COMPANY (US) 1994-12-08 WO disclosed
US-5288835-A 4,4*-bis(hydroxyphenoxy)biphenyl as one of the monomer E. I. DU PONT DE NEMOURS AND COMPANY (US) 1994-02-22 US disclosed