Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 4/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8969519 | 0.87 | KLK7 (0.49) | KLK7ACHEGLA | |
| SCHEMBL8969356 | 0.81 | KLK7 (0.39) | KLK7 | |
| SCHEMBL9382150 | 0.71 | ACHE (0.51) | KLK7ACHE | |
| SCHEMBL8969407 | 0.69 | ACHE (0.51) | KLK7ACHE | |
| SCHEMBL8969429 | 0.69 | KLK7 (0.56) | KLK7ACHE | |
| SCHEMBL9380049 | 0.69 | ACHE (0.51) | KLK7ACHE | |
| SCHEMBL8969296 | 0.67 | ACHE (0.35) | KLK7ACHE | |
| SCHEMBL8970190 | 0.65 | ACHE (0.57) | ACHE | |
| SCHEMBL8969149 | 0.64 | ACHE (0.59) | ACHE | |
| SCHEMBL9380160 | 0.62 | ACHE (0.38) | KLK7ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| EP-0597956-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1994-05-25 | — | — | EP | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |