Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8969519 | 0.87 | KLK7 (0.49) | KLK7 | |
| SCHEMBL8969197 | 0.81 | KLK7 (0.42) | KLK7 | |
| SCHEMBL8969251 | 0.69 | ACHE (0.55) | KLK7 | |
| SCHEMBL8969429 | 0.66 | KLK7 (0.56) | KLK7 | |
| SCHEMBL9382150 | 0.66 | ACHE (0.51) | KLK7 | |
| SCHEMBL9380049 | 0.66 | ACHE (0.51) | KLK7 | |
| SCHEMBL8969794 | 0.65 | ACHE (0.60) | — | |
| SCHEMBL9380132 | 0.63 | ACHE (0.39) | KLK7 | |
| SCHEMBL9383664 | 0.63 | ACHE (0.45) | KLK7 | |
| SCHEMBL9380285 | 0.61 | ACHE (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| EP-0597956-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1994-05-25 | — | — | EP | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |