Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 15/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8968696 | 0.94 | ACHE (0.50) | ACHE | |
| SCHEMBL8969046 | 0.89 | ACHE (0.47) | ACHE | |
| SCHEMBL8968400 | 0.85 | ACHE (0.43) | ACHE | |
| SCHEMBL8969672 | 0.84 | ACHE (0.39) | ACHE | |
| SCHEMBL8968248 | 0.82 | ACHE (0.46) | ACHE | |
| SCHEMBL8968411 | 0.82 | ACHE (0.47) | ACHE | |
| SCHEMBL8968253 | 0.78 | ACHE (0.38) | ACHE | |
| SCHEMBL8969638 | 0.76 | ACHE (0.47) | ACHE | |
| SCHEMBL8968627 | 0.75 | ACHE (0.42) | ACHE | |
| SCHEMBL8969102 | 0.74 | MGLL (0.47) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |