SCHEMBL8969239

SCHEMBL8969239

CCCCCCCCOc1ccc(-c2ccc(-c3ccc(CCCCC4CCC(CCCCC)CO4)c(F)c3)cc2)c(F)c1F

nearest known ligand 0.35

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 14/20 0.35
CNR1 P21554 8/20 0.35
SLC6A2 P23975 3/20 0.35
SLC6A4 P31645 3/20 0.35
SLC6A3 Q01959 3/20 0.35
GBA1 P04062 2/20 0.32
LCT P09848 2/20 0.32
UGCG Q16739 2/20 0.32
GBA2 Q9HCG7 2/20 0.32
MGAM O43451 1/20 0.32
SI P14410 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8969516 0.95 SLC6A2 (0.36) CNR2SLC6A2SLC6A4SLC6A3
SCHEMBL8969298 0.92 CNR2 (0.34) CNR2CNR1SLC6A2SLC6A4SLC6A3
SCHEMBL8969304 0.92 CNR2 (0.34) CNR2CNR1SLC6A2SLC6A4SLC6A3
SCHEMBL8969132 0.92 NAAA (0.35) SLC6A2SLC6A4SLC6A3
SCHEMBL8969744 0.89 CNR2 (0.33) CNR2CNR1
SCHEMBL8969709 0.89 SLC6A2 (0.34) CNR2CNR1SLC6A2SLC6A4SLC6A3
SCHEMBL8969598 0.88 S1PR1 (0.33) CNR2CNR1
SCHEMBL8969305 0.87 RARB (0.41) CNR2CNR1SLC6A2SLC6A4SLC6A3
SCHEMBL8969240 0.85 NAAA (0.39) CNR2CNR1SLC6A2SLC6A4SLC6A3
SCHEMBL10301559 0.84 CNR2 (0.41) CNR2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8187494-B2 Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device JNC CORPORATION (JP) 2012-05-29 US disclosed