Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 9/20 | 0.54 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8969229 | 0.78 | ACHE (0.42) | ACHEHSD11B1HSD11B2HTTALDH1A1 | |
| SCHEMBL8968337 | 0.74 | ACHE (0.56) | ACHEHTTALDH1A1 | |
| SCHEMBL8968620 | 0.72 | KLK7 (0.37) | ACHE | |
| SCHEMBL8969296 | 0.71 | ACHE (0.35) | ACHESLC6A3 | |
| SCHEMBL8968453 | 0.70 | ACHE (1.00) | ACHEALDH1A1 | |
| SCHEMBL8968773 | 0.69 | ACHE (0.97) | ACHEALDH1A1 | |
| SCHEMBL8970444 | 0.68 | ACHE (0.70) | ACHEHTTKDM4EALDH1A1HPGD | |
| SCHEMBL9382150 | 0.68 | ACHE (0.51) | ACHE | |
| SCHEMBL8969833 | 0.66 | ACHE (1.00) | ACHEHTTKDM4EALDH1A1 | |
| SCHEMBL24330116 | 0.65 | ACHE (0.67) | ACHEHTTKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |