Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 18/20 | 0.62 |
| ▸ | MMP2 | P08253 | 6/20 | 0.62 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.57 |
| ▸ | MMP12 | P39900 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8772607 | 0.89 | MMP13 (0.64) | MMP13MMP2FDFT1MMP12 | |
| SCHEMBL8968959 | 0.89 | MMP13 (0.65) | MMP13MMP2FDFT1 | |
| Hydrochloric Acid SCHEMBL8772652 | 0.88 | MMP13 (0.62) | MMP13MMP2FDFT1MMP12 | |
| SCHEMBL8772564 | 0.87 | MMP13 (0.61) | MMP13MMP2FDFT1MMP12 | |
| SCHEMBL8969719 | 0.85 | MMP13 (0.57) | MMP13MMP2FDFT1 | |
| SCHEMBL9433014 | 0.85 | MMP13 (0.58) | MMP13MMP2FDFT1MMP12 | |
| SCHEMBL8973148 | 0.85 | FDFT1 (0.60) | MMP13MMP2FDFT1 | |
| SCHEMBL8968494 | 0.84 | MMP13 (0.51) | MMP13MMP2FDFT1 | |
| SCHEMBL8969567 | 0.84 | FDFT1 (0.51) | MMP13MMP2FDFT1 | |
| SCHEMBL9432559 | 0.84 | MMP13 (0.51) | MMP13MMP2FDFT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1121718-A | Heterocyclic derivatives | ZENECA LTD (GB) | 1996-05-01 | — | — | CN | disclosed |
| EP-0696284-A1 | HETEROCYCLIC DERIVATIVES | ZENECA LIMITED (GB) | 1996-02-14 | — | — | EP | disclosed |
| WO-1994025459-A1 | HETEROCYCLIC DERIVATIVES | ZENECA LIMITED (GB) | 1994-11-10 | — | — | WO | disclosed |