Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 18/20 | 0.65 |
| ▸ | MMP2 | P08253 | 5/20 | 0.62 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8969313 | 0.89 | MMP13 (0.62) | MMP13MMP2FDFT1 | |
| SCHEMBL9284982 | 0.88 | MMP13 (0.54) | MMP13MMP2 | |
| SCHEMBL8772607 | 0.88 | MMP13 (0.64) | MMP13MMP2FDFT1 | |
| Hydrochloric Acid SCHEMBL8772652 | 0.87 | MMP13 (0.62) | MMP13MMP2FDFT1 | |
| SCHEMBL27540947 | 0.86 | MMP13 (0.49) | MMP13MMP2FDFT1 | |
| SCHEMBL3259548 | 0.86 | MMP13 (0.63) | MMP13MMP2FDFT1 | |
| SCHEMBL8971168 | 0.84 | MMP13 (0.50) | MMP13MMP2FDFT1 | |
| SCHEMBL8931446 | 0.83 | MMP13 (0.61) | MMP13MMP2FDFT1 | |
| SCHEMBL8931430 | 0.82 | MMP13 (0.66) | MMP13MMP2FDFT1 | |
| SCHEMBL8969946 | 0.80 | FDFT1 (0.73) | MMP13MMP2FDFT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1121718-A | Heterocyclic derivatives | ZENECA LTD (GB) | 1996-05-01 | — | — | CN | disclosed |
| EP-0696284-A1 | HETEROCYCLIC DERIVATIVES | ZENECA LIMITED (GB) | 1996-02-14 | — | — | EP | disclosed |
| WO-1994025459-A1 | HETEROCYCLIC DERIVATIVES | ZENECA LIMITED (GB) | 1994-11-10 | — | — | WO | disclosed |