Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 2/20 | 0.41 |
| ▸ | PPP5C | P53041 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 7/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8970413 | 1.00 | GBA1 (0.41) | GBA1PPP5CS1PR3ALDH1A1PPARG | |
| SCHEMBL8970931 | 1.00 | GBA1 (0.41) | GBA1PPP5CS1PR3ALDH1A1PPARG | |
| SCHEMBL8969092 | 1.00 | GBA1 (0.41) | GBA1PPP5CS1PR3ALDH1A1PPARG | |
| SCHEMBL8970773 | 1.00 | GBA1 (0.41) | GBA1PPP5CS1PR3ALDH1A1PPARG | |
| SCHEMBL8969022 | 0.98 | PPP5C (0.41) | GBA1PPP5CS1PR3ALDH1A1PPARG | |
| SCHEMBL8970164 | 0.94 | PPP5C (0.46) | GBA1PPP5CS1PR3ALDH1A1HCAR2 | |
| SCHEMBL8969140 | 0.87 | GRM2 (0.35) | PPP5C | |
| SCHEMBL8970275 | 0.80 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL8969230 | 0.79 | NAAA (0.49) | NAAA | |
| SCHEMBL8969975 | 0.78 | PPARG (0.45) | PPARGNAAAHCAR2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376294-B1 | Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions | HITACHI LTD (JP) | 1996-03-13 | — | — | EP | disclosed |
| US-5370821-A | Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-12-06 | — | — | US | disclosed |
| US-5269965-A | Optically active compounds, liquid crystal compositions comprising said compounds and liquid crystal optical modulators using said compositions | TAKEDA CHEMICAL INDUSTRIES (JP) | 1993-12-14 | — | — | US | disclosed |
| EP-0376294-A1 | Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions | HITACHI, LTD. (JP) | 1990-07-04 | — | — | EP | disclosed |