Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | GSR | P00390 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GPR88 | Q9GZN0 | 2/20 | 0.32 |
| ▸ | NPY1R | P25929 | 1/20 | 0.31 |
| ▸ | NPY2R | P49146 | 1/20 | 0.31 |
| ▸ | NPY4R | P50391 | 1/20 | 0.31 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8970682 | 0.98 | CA1 (0.35) | CA1CA2CA4GSRTSHR | |
| SCHEMBL8970614 | 0.98 | CA1 (0.35) | CA1CA2CA4GSRTSHR | |
| SCHEMBL8970233 | 0.97 | TSHR (0.33) | CA1CA2CA4GSRTSHR | |
| SCHEMBL3179737 | 0.87 | TSHR (0.34) | TSHRGPR88 | |
| SCHEMBL12015275 | 0.80 | CA1 (0.34) | CA1CA2CA4GSR | |
| SCHEMBL8970573 | 0.80 | GSR (0.38) | CA1CA2CA4GSRNPY1R | |
| SCHEMBL8970488 | 0.78 | GSR (0.40) | CA1CA2CA4GSRNPY1R | |
| SCHEMBL8969037 | 0.78 | GSR (0.40) | CA1CA2CA4GSRNPY1R | |
| SCHEMBL8970583 | 0.78 | GPR88 (0.36) | GPR88 | |
| SCHEMBL8969008 | 0.76 | GPR88 (0.37) | GPR88 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376294-B1 | Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions | HITACHI LTD (JP) | 1996-03-13 | — | — | EP | disclosed |
| US-5370821-A | Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-12-06 | — | — | US | disclosed |
| US-5269965-A | Optically active compounds, liquid crystal compositions comprising said compounds and liquid crystal optical modulators using said compositions | TAKEDA CHEMICAL INDUSTRIES (JP) | 1993-12-14 | — | — | US | disclosed |
| EP-0376294-A1 | Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions | HITACHI, LTD. (JP) | 1990-07-04 | — | — | EP | disclosed |