SCHEMBL8970614

SCHEMBL8970614

CCCC(C)COC1CCCCCCC1O

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA4 P22748 1/20 0.35
GSR P00390 2/20 0.35
GPR88 Q9GZN0 2/20 0.33
TSHR P16473 1/20 0.32
NPY1R P25929 1/20 0.30
NPY2R P49146 1/20 0.30
NPY4R P50391 1/20 0.30
NPY5R Q15761 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8970682 1.00 CA1 (0.35) CA1CA2CA4GSRGPR88
SCHEMBL8969503 0.98 CA1 (0.36) CA1CA2CA4GSRGPR88
SCHEMBL8970233 0.95 TSHR (0.33) CA1CA2CA4GSRGPR88
SCHEMBL3179737 0.86 TSHR (0.34) GPR88TSHR
SCHEMBL8969037 0.80 GSR (0.40) CA1CA2CA4GSRNPY1R
SCHEMBL8970488 0.80 GSR (0.40) CA1CA2CA4GSRNPY1R
SCHEMBL12015275 0.79 CA1 (0.34) CA1CA2CA4GSR
SCHEMBL8969008 0.78 GPR88 (0.37) GPR88
SCHEMBL8970288 0.78 GPR88 (0.37) GPR88
SCHEMBL8970573 0.78 GSR (0.38) CA1CA2CA4GSRNPY1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0376294-B1 Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions HITACHI LTD (JP) 1996-03-13 EP disclosed
US-5370821-A Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1994-12-06 US disclosed
US-5269965-A Optically active compounds, liquid crystal compositions comprising said compounds and liquid crystal optical modulators using said compositions TAKEDA CHEMICAL INDUSTRIES (JP) 1993-12-14 US disclosed
EP-0376294-A1 Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions HITACHI, LTD. (JP) 1990-07-04 EP disclosed