Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | CCR3 | P51677 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 4/20 | 0.49 |
| ▸ | DRD4 | P21917 | 4/20 | 0.49 |
| ▸ | DRD3 | P35462 | 4/20 | 0.49 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | TACR1 | P25103 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8563831 | 0.99 | KDM4E (0.62) | KDM4EKMT2ACCR3SIGMAR1DRD2 | |
| SCHEMBL4680438 | 0.92 | KDM4E (0.70) | KDM4EKMT2ACCR3SIGMAR1DRD2 | |
| SCHEMBL30596349 | 0.92 | KDM4E (0.70) | KDM4EKMT2ACCR3SIGMAR1DRD2 | |
| SCHEMBL11450342 | 0.86 | OPRM1 (0.61) | KDM4EKMT2ACCR3DRD2DRD4 | |
| Hydrochloric Acid SCHEMBL11437813 | 0.85 | OPRM1 (0.60) | KDM4EKMT2ACCR3DRD2DRD4 | |
| SCHEMBL5242779 | 0.85 | OPRL1 (0.67) | KDM4EKMT2ACCR3SIGMAR1DRD2 | |
| SCHEMBL8959960 | 0.85 | KMT2A (0.57) | KDM4EKMT2ACCR3SIGMAR1DRD2 | |
| SCHEMBL13543993 | 0.84 | CCR3 (0.72) | KDM4EKMT2ACCR3SIGMAR1DRD2 | |
| Hydrochloric Acid SCHEMBL10750648 | 0.84 | POLB (0.68) | KDM4EKMT2ACCR3SIGMAR1DRD2 | |
| Hydrochloric Acid SCHEMBL9310932 | 0.84 | KMT2A (0.59) | KDM4EKMT2ACCR3SIGMAR1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700386-A1 | NEUROKININ RECEPTOR ANTAGONISTS | SANOFI (FR) | 1996-03-13 | — | — | EP | disclosed |
| WO-1995026338-A1 | NEUROKININ RECEPTOR ANTAGONISTS | SANOFI (FR) | 1995-10-05 | — | — | WO | disclosed |