Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.70 |
| ▸ | CCR3 | P51677 | 1/20 | 0.60 |
| ▸ | OPRL1 | P41146 | 6/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | DRD4 | P21917 | 4/20 | 0.55 |
| ▸ | DRD3 | P35462 | 4/20 | 0.55 |
| ▸ | DRD2 | P14416 | 3/20 | 0.55 |
| ▸ | TACR1 | P25103 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4680438 | 1.00 | KDM4E (0.70) | KDM4EKMT2ACCR3OPRL1POLB | |
| SCHEMBL8969668 | 0.92 | KDM4E (0.60) | KDM4EKMT2ACCR3OPRL1POLB | |
| SCHEMBL13543993 | 0.92 | CCR3 (0.72) | KDM4EKMT2ACCR3OPRL1POLB | |
| Hydrochloric Acid SCHEMBL8563831 | 0.91 | KDM4E (0.62) | KDM4EKMT2ACCR3OPRL1POLB | |
| SCHEMBL667088 | 0.85 | ALDH1A1 (0.57) | KDM4EKMT2ACCR3OPRL1DRD4 | |
| SCHEMBL29087358 | 0.85 | CCR3 (0.83) | KDM4EKMT2ACCR3OPRL1POLB | |
| SCHEMBL10226080 | 0.84 | OPRL1 (0.81) | KDM4EKMT2ACCR3OPRL1POLB | |
| SCHEMBL1820347 | 0.83 | KDM4E (0.69) | KDM4EKMT2ACCR3OPRL1POLB | |
| SCHEMBL8298555 | 0.82 | TACR1 (0.75) | KDM4EKMT2ACCR3OPRL1POLB | |
| SCHEMBL3115662 | 0.82 | DRD2 (0.49) | KDM4EKMT2AOPRL1DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116806217-A | Substituted cyclic modulators of protein phosphatase 2A (PP 2A) and methods of use thereof | 拉帕塔疗法公司 | 2023-09-26 | — | — | CN | disclosed |