Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.40 |
| ▸ | SPR | P35270 | 2/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8968451 | 0.82 | ACHE (0.62) | ACHECHRM4 | |
| SCHEMBL8969316 | 0.82 | ACHE (0.32) | ACHE | |
| SCHEMBL8968195 | 0.81 | ACHE (0.41) | ACHESPR | |
| SCHEMBL8968694 | 0.80 | ACHE (0.62) | ACHECHRM4 | |
| SCHEMBL8968233 | 0.79 | ACHE (0.57) | ACHE | |
| SCHEMBL8969421 | 0.78 | ACHE (0.63) | ACHE | |
| Hydrochloric Acid SCHEMBL8969536 | 0.78 | ACHE (0.56) | ACHE | |
| SCHEMBL29869033 | 0.77 | ACHE (0.66) | ACHE | |
| SCHEMBL4448665 | 0.77 | ACHE (0.66) | ACHE | |
| Hydrochloric Acid SCHEMBL8968390 | 0.76 | ACHE (0.64) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| EP-0597956-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1994-05-25 | — | — | EP | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |