Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 13/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8969738 | 0.90 | ACHE (0.46) | ACHEALDH1A1SMN1; SMN2HTTSUV39H2 | |
| SCHEMBL8968711 | 0.85 | ACHE (0.47) | ACHEALDH1A1SMN1; SMN2HTTSUV39H2 | |
| SCHEMBL8968908 | 0.80 | ACHE (0.46) | ACHEALDH1A1SMN1; SMN2HTTMEN1 | |
| SCHEMBL8969109 | 0.80 | ACHE (0.50) | ACHEALDH1A1SMN1; SMN2HTTMEN1 | |
| SCHEMBL8970082 | 0.80 | ACHE (0.50) | ACHEALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8969467 | 0.80 | ACHE (0.47) | ACHEALDH1A1SMN1; SMN2HTTSUV39H2 | |
| SCHEMBL8968331 | 0.80 | ACHE (0.47) | ACHEALDH1A1SMN1; SMN2HTTSUV39H2 | |
| SCHEMBL8968930 | 0.80 | ACHE (0.47) | ACHEALDH1A1SMN1; SMN2HTTSUV39H2 | |
| SCHEMBL8969642 | 0.79 | ACHE (0.48) | ACHEALDH1A1SMN1; SMN2HTTMEN1 | |
| SCHEMBL8968995 | 0.79 | ACHE (0.45) | ACHEHTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |