Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 14/20 | 0.50 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
| ▸ | CHKA | P35790 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8969676 | 0.90 | ACHE (0.50) | ACHEBCHECHKAALDH1A1LMNA | |
| SCHEMBL8970605 | 0.85 | ACHE (0.55) | ACHEBCHEALDH1A1LMNAMAPT | |
| SCHEMBL8968341 | 0.81 | ACHE (0.53) | ACHEBCHEALDH1A1LMNAHPGD | |
| SCHEMBL8969109 | 0.81 | ACHE (0.50) | ACHEBCHEALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL8969839 | 0.80 | ACHE (0.46) | ACHEALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8969738 | 0.80 | ACHE (0.46) | ACHEALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8969790 | 0.80 | ACHE (0.51) | ACHEBCHEALDH1A1LMNAHPGD | |
| SCHEMBL8968295 | 0.79 | ACHE (0.47) | ACHEBCHECHKAALDH1A1LMNA | |
| SCHEMBL8969580 | 0.78 | ACHE (0.49) | ACHEBCHEALDH1A1LMNAHRH3 | |
| SCHEMBL8968331 | 0.78 | ACHE (0.47) | ACHEALDH1A1MAPTMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |