Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 14/20 | 0.69 |
| ▸ | KLK7 | P49862 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8969833 | 0.79 | ACHE (1.00) | ACHEKDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL29869033 | 0.70 | ACHE (0.66) | ACHEKLK7L3MBTL1MEN1KMT2A | |
| SCHEMBL4448665 | 0.70 | ACHE (0.66) | ACHEKLK7L3MBTL1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8968390 | 0.69 | ACHE (0.64) | ACHEKLK7L3MBTL1MEN1KMT2A | |
| SCHEMBL8969421 | 0.68 | ACHE (0.63) | ACHEKLK7L3MBTL1MEN1KMT2A | |
| SCHEMBL8970444 | 0.67 | ACHE (0.70) | ACHEKDM4EMEN1KMT2AHPGD | |
| SCHEMBL8969429 | 0.67 | KLK7 (0.56) | ACHEKLK7NPC1ALDH1A1RAB9A | |
| SCHEMBL8969229 | 0.67 | ACHE (0.42) | ACHEKLK7L3MBTL1HPGDNPC1 | |
| SCHEMBL8968233 | 0.63 | ACHE (0.57) | ACHEKLK7L3MBTL1MEN1KMT2A | |
| SCHEMBL8969695 | 0.62 | ACHE (0.59) | ACHEMEN1KMT2AALDH1A1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| EP-0597956-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1994-05-25 | — | — | EP | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |