Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 16/20 | 0.56 |
| ▸ | PRKCA | P17252 | 3/20 | 0.47 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11993693 | 0.96 | PRKCQ (0.52) | PRKCQPRKCAPRKCDHTR1AHTR2A | |
| SCHEMBL9010807 | 0.89 | PRKCQ (0.54) | PRKCQPRKCAPRKCDPIM1HSD17B14 | |
| SCHEMBL8969919 | 0.87 | PRKCQ (0.52) | PRKCQPRKCAPRKCD | |
| SCHEMBL8970237 | 0.86 | PRKCQ (0.58) | PRKCQPRKCAPRKCDHSD17B14 | |
| SCHEMBL11993696 | 0.85 | PRKCQ (0.49) | PRKCQPRKCAPRKCDHTR1AHTR2A | |
| SCHEMBL9008438 | 0.85 | PRKCQ (0.50) | PRKCQPRKCAPRKCDPIM1 | |
| SCHEMBL8969935 | 0.81 | PRKCQ (0.54) | PRKCQPRKCAPRKCD | |
| SCHEMBL13857242 | 0.81 | PRKCQ (0.47) | PRKCQPRKCAPRKCDPIM1HTR1A | |
| SCHEMBL8185355 | 0.81 | PRKCQ (0.71) | PRKCQPRKCAPRKCDPIM1 | |
| SCHEMBL16071357 | 0.81 | PRKCQ (0.53) | PRKCQPRKCAPRKCDHSD17B14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8188071-B2 | Amino substituted pyridines as potent kinase inhibitors | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2012-05-29 | — | — | US | disclosed |