Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PEPD | P12955 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8970397 | 1.00 | SMN1; SMN2 (0.36) | SMN1; SMN2ALDH1A1PEPDMAPTHTT | |
| SCHEMBL8163124 | 0.98 | ALDH1A1 (0.38) | SMN1; SMN2ALDH1A1PEPD | |
| SCHEMBL8971125 | 0.94 | PEPD (0.41) | SMN1; SMN2ALDH1A1PEPD | |
| SCHEMBL8970379 | 0.85 | PPM1B (0.38) | PEPD | |
| SCHEMBL8969495 | 0.85 | PPM1B (0.38) | PEPD | |
| SCHEMBL8970440 | 0.83 | PPM1B (0.39) | PEPD | |
| SCHEMBL8969601 | 0.82 | PPP5C (0.49) | — | |
| SCHEMBL8970033 | 0.82 | PPP5C (0.49) | — | |
| SCHEMBL8970439 | 0.81 | PPP5C (0.44) | — | |
| SCHEMBL8970248 | 0.81 | PPP5C (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376294-B1 | Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions | HITACHI LTD (JP) | 1996-03-13 | — | — | EP | disclosed |
| US-5370821-A | Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-12-06 | — | — | US | disclosed |
| US-5269965-A | Optically active compounds, liquid crystal compositions comprising said compounds and liquid crystal optical modulators using said compositions | TAKEDA CHEMICAL INDUSTRIES (JP) | 1993-12-14 | — | — | US | disclosed |
| EP-0376294-A1 | Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions | HITACHI, LTD. (JP) | 1990-07-04 | — | — | EP | disclosed |