SCHEMBL8970166

SCHEMBL8970166

CC(C)=NOC(=O)C1CC1

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
RBBP9 O75884 1/20 0.41
RAB9A P51151 4/20 0.39
NPC1 O15118 3/20 0.39
CASP3 P42574 1/20 0.39
SENP8 Q96LD8 1/20 0.39
SENP7 Q9BQF6 1/20 0.39
SENP6 Q9GZR1 1/20 0.39
ATM Q13315 1/20 0.38
LMNA P02545 1/20 0.37
PKM P14618 1/20 0.35
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
MIF P14174 3/20 0.33
SMN1; SMN2 Q16637 1/20 0.32
ALDH1A1 P00352 2/20 0.32
POLB P06746 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14370800 0.89 RBBP9 (0.51) RBBP9RAB9ANPC1CASP3SENP8
SCHEMBL2303013 0.84 RAB9A (0.41) RBBP9RAB9ANPC1CASP3SENP8
SCHEMBL12328526 0.73 RBBP9 (0.49) RBBP9RAB9ANPC1CASP3SENP8
SCHEMBL9507310 0.72
SCHEMBL3154358 0.70 RAB9A (0.39) RBBP9RAB9ANPC1CASP3SENP8
SCHEMBL19476974 0.70 ALDH1A1 (0.40) RBBP9RAB9ANPC1CASP3SENP8
SCHEMBL19462062 0.70 ALDH1A1 (0.40) RBBP9RAB9ANPC1CASP3SENP8
SCHEMBL5094316 0.69
SCHEMBL988752 0.68 TP53 (0.48) SMN1; SMN2ALDH1A1POLB
SCHEMBL988753 0.68 TP53 (0.48) SMN1; SMN2ALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5521145-A Iminothiazoline derivatives and herbicides containing them as active ingredients SUMITOMO CHEMICAL COMPANY, LTD. (JP) 1996-05-28 US disclosed
EP-0683160-A1 Iminothiazoline derivatives and herbicides containing them as active ingredients SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-11-22 EP disclosed