Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL540173 | 0.86 | MAPT (0.40) | ARALDH1A1LMNAMAPTALOX12 | |
| SCHEMBL10205675 | 0.86 | AR (0.32) | AR | |
| SCHEMBL539945 | 0.86 | AR (0.32) | AR | |
| SCHEMBL540309 | 0.83 | AR (0.46) | AR | |
| SCHEMBL6112946 | 0.82 | C1S (0.36) | ARALDH1A1LMNAMAPTALOX12 | |
| SCHEMBL539835 | 0.81 | KCNJ6 (0.33) | ARLMNAMAPT | |
| SCHEMBL8975787 | 0.80 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL540031 | 0.80 | AR (0.36) | AR | |
| SCHEMBL8931774 | 0.79 | MEN1 (0.37) | ARALDH1A1LMNAMAPTALOX12 | |
| SCHEMBL541199 | 0.79 | KCNH2 (0.41) | ARSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120232278-A1 | Insecticidal Aryl Pyrrolidines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2012-09-13 | — | — | US | disclosed |
| US-8188122-B2 | Insecticidal aryl pyrrolidines | BAYER CROPSCIENCE AG (DE) | 2012-05-29 | — | — | US | disclosed |
| US-20110082175-A1 | INSECTICIDAL ARYL PYRROLIDINES | BAYER CROPSCIENCE AG (DE) | 2011-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120232278-A1 | Insecticidal Aryl Pyrrolidines | DDT, ITPR3, CYP51A1 | AR 4257/4885ALDH1A1 261/4885LMNA 4668/4885 |
| US-20110082175-A1 | INSECTICIDAL ARYL PYRROLIDINES | DDT, ITPR3, CYP51A1 | AR 4257/4885ALDH1A1 261/4885LMNA 4668/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.