Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPM1B | O75688 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8970499 | 0.85 | PPM1B (0.45) | PPM1BPTPN1PPP1CCALDH1A1 | |
| SCHEMBL19342535 | 0.83 | SOAT1 (0.35) | PPM1BPTPN1PPP1CCALDH1A1CA12 | |
| SCHEMBL8969294 | 0.82 | ALDH1A1 (0.41) | PPM1BPTPN1PPP1CCALDH1A1TSHR | |
| SCHEMBL8970154 | 0.81 | PPARG (0.43) | ALDH1A1TSHR | |
| SCHEMBL8970421 | 0.81 | CYP1A2 (0.36) | PPM1BPTPN1PPP1CCALDH1A1CA12 | |
| SCHEMBL8971023 | 0.80 | RAB9A (0.39) | ALDH1A1TSHR | |
| SCHEMBL9033901 | 0.80 | ALDH1A1 (0.39) | PPM1BPTPN1PPP1CCALDH1A1CA12 | |
| SCHEMBL9033905 | 0.80 | ALDH1A1 (0.39) | PPM1BPTPN1PPP1CCALDH1A1CA12 | |
| SCHEMBL9033895 | 0.80 | ALDH1A1 (0.39) | PPM1BPTPN1PPP1CCALDH1A1CA12 | |
| SCHEMBL8969975 | 0.80 | PPARG (0.45) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376294-B1 | Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions | HITACHI LTD (JP) | 1996-03-13 | — | — | EP | disclosed |
| US-5370821-A | Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-12-06 | — | — | US | disclosed |
| US-5269965-A | Optically active compounds, liquid crystal compositions comprising said compounds and liquid crystal optical modulators using said compositions | TAKEDA CHEMICAL INDUSTRIES (JP) | 1993-12-14 | — | — | US | disclosed |
| EP-0376294-A1 | Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions | HITACHI, LTD. (JP) | 1990-07-04 | — | — | EP | disclosed |